ACER1 (Alkaline Ceramidase 1, ACER1)
Short Description: Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine (Houben et al., 2006 [PubMed 16477081]\; Sun et al., 2008 [PubMed 17713573]).[supplied by OMIM, Jul 2010].
More information related to gene ACER1.
More information related to gene ACER1.
Products related to ACER1 Gene:
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56 results
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Alkaline Ceramidase 1 (ACER1)
- NCBI Accession:
- NM_133492
- Gene ID:
- 125981 (Human, ACER1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4941817
OriGene rc211332
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Alkaline Ceramidase 1 (ACER1)
- NCBI Accession:
- NM_133492,NP_597999
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5386466
$297.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 10 Business Days
OriGene mc212348
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Alkaline Ceramidase 1 (ACER1)
- NCBI Accession:
- NM_175731,NP_783858
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3308516
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
OriGene rn204668
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Alkaline Ceramidase 1 (ACER1)
- NCBI Accession:
- NM_001106875,NP_001100345
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3308517
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
OriGene sc305969
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Alkaline Ceramidase 1 (ACER1)
- NCBI Accession:
- NM_133492,NP_597999
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3320603
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
OriGene rr204668
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Alkaline Ceramidase 1 (ACER1)
- NCBI Accession:
- NM_001106875,NP_001100345
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5386467
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
OriGene rg211332
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Alkaline Ceramidase 1 (ACER1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5386465
$484.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 31 Business Days
OriGene sr407826
RNAi
ACER1
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Alkaline Ceramidase 1
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3281778
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene sr504382
RNAi
ACER1
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Alkaline Ceramidase 1
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3354296
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene sr314889
RNAi
ACER1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Alkaline Ceramidase 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3311891
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
Synonyms and alternative names related to ACER1
- alkaline ceramidase 1 (ACER1)
- alkaline ceramidase 1 (acer1)
- alkaline ceramidase 1 (Acer1)
- 2310024P18Rik
- AI662009
- ALKCDase1
- Alkcdase1
- ASAH3
- asah3
- Asah3
- Cer1
- zgc:110285
Gene-IDs for different species
Protein level used designations for ACER1
- N-acylsphingosine amidohydrolase (alkaline ceramidase) 3
- alkaline ceramidase 1
- N-acylsphingosine amidohydrolase 3
- acylsphingosine deacylase 3
- alkCDase 1
- alkaline CDase 1
- alkaline cdase 1
- maCER1
Proteomics products related to ACER1 Gene
Other products related to ACER1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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