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AIF (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1, AIFM1)

Short Description: This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, May 2010].
More information related to gene AIF.

Products related to AIF Gene:

81 results

OriGene tf711321 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3491597
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene kn301038 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3245722
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 10 to 13 Business Days
OriGene kn410668 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3245721
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sc324345 cDNA PExp Mammalian Expression Vector pCMV6-AC Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_145812,NP_665811
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient, Stable
Catalog No. ABIN3319556
$562.32
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sc325773 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_001130847,NP_001124319
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3320737
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene mc228455 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_001290364,NP_001277293
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3309244
$617.76
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene rn212423 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_031356,NP_112646
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3309245
$621.72
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene mc219720 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019,NP_036149
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3309243
$903.87
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sc100268 cDNA PExp Mammalian Expression Vector pCMV6-XL4 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_145813,NP_665812
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL4
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3376966
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sc111098 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_004208,NP_004199
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3382415
$566.28
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-U6-sgRNA-PGK-Neo
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCas-Guide
    • pCMV6-AC
    • pCMV6-XL4
    • pCMV6-XL5
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • SFFV Promoter
    • PGK Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to AIF

  • apoptosis inducing factor mitochondria associated 1 (AIFM1)
  • allograft inflammatory factor 1 (AIF1)
  • Apoptosis inducing factor (AIF)
  • apoptosis-inducing factor 1, mitochondrial (LOC412212)
  • apoptosis inducing factor (aif)
  • apoptosis inducing factor, mitochondria associated 1 (AIFM1)
  • apoptosis inducing factor, mitochondria associated 1 (aifm1)
  • apoptosis-inducing factor, mitochondrion-associated, 1 (AIFM1)
  • apoptosis inducing factor mitochondria associated 1 (aifm1)
  • apoptosis-inducing factor, mitochondrion-associated 1 (Aifm1)
  • apoptosis inducing factor, mitochondria associated 1 (Aifm1)
  • apoptosis-inducing factor, mitochondrion-associated 1 (aifm1)
  • AIF
  • aif
  • Aif
  • AIFM1
  • AIFsh2
  • CG7263
  • CMTX4
  • COWCK
  • COXPD6
  • DDBDRAFT_0187853
  • DDBDRAFT_0191137
  • DDB_0187853
  • DDB_0191137
  • DmAIF
  • Dmel\\CG7263
  • GB16024
  • Hq
  • mAIF
  • PCD8
  • PDCD8
  • pdcd8
  • Pdcd8
  • zgc:91994

Gene-IDs for different species

Protein level used designations for AIF

  • apoptosis-inducing factor 1, mitochondrial
  • programmed cell death 8 (apoptosis-inducing factor)
  • striatal apoptosis-inducing factor
  • AIF-1
  • anti-inflammatory factor 1
  • daintain
  • AIF-PA
  • AIF-PB
  • AIF-PC
  • CG7263-PA
  • CG7263-PB
  • CG7263-PC
  • apoptosis inducing factor
  • programmed cell death 8
  • apoptosis-inducing factor, mitochondrion-associated, 1
  • mammary apoptosis inducing factor
  • flavoprotein and apoptosis inductor
  • apoptosis-inducing factor 1, mitochondrial-like
  • harlequin
  • programmed cell death protein 8
Other products related to AIF such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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