ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial), ALDH2)
Short Description: This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2011].
More information related to gene ALDH2.
More information related to gene ALDH2.
Products related to ALDH2 Gene:
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OriGene rc200505l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2)
- NCBI Accession:
- NM_000690,NP_000681
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5392144
$773.19
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10 μg
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Synonyms and alternative names related to ALDH2
- aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 (aldh2.1)
- aldehyde dehydrogenase 2 family (mitochondrial) L homeolog (aldh2.L)
- aldehyde dehydrogenase 2 family (mitochondrial) (aldh2)
- aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2)
- aldehyde dehydrogenase 2 (aldh2)
- aldehyde dehydrogenase (RHA1_RS43090)
- aldehyde dehydrogenase (NAD(+)) (aldH2)
- hypothetical protein (OE_RS03015)
- aldehyde dehydrogenase (aldH2)
- aldehyde dehydrogenase 2 family (mitochondrial) (Aldh2)
- aldehyde dehydrogenase 2, mitochondrial (Aldh2)
- Ahd-5
- Ahd5
- aldh-e2
- ALDH-E2
- aldh2
- aldh2a
- aldhi
- ALDHI
- aldm
- ALDM
- MGC80785
- rf2b
- zgc:63786
Gene-IDs for different species
Protein level used designations for ALDH2
- aldehyde dehydrogenase 2
- aldehyde dehydrogenase 2 family (mitochondrial)
- aldehyde dehydrogenase 2 family (mitochondrial)a
- aldehyde dehydrogenase 2.1
- mitochondrial aldehyde dehydrogenase 2
- ALDH2B6
- mitochondrial aldehyde dehydrogenase RF2B
- aldehyde dehydrogenase
- aldehyde dehydrogenase (NAD(+))
- ALDH class 2
- ALDH-E2
- aldehyde dehydrogenase, mitochondrial
- aldehyde dehydrogenase, mitochondrial-like
- acetaldehyde dehydrogenase 2
- liver mitochondrial ALDH
- nucleus-encoded mitochondrial aldehyde dehydrogenase 2
- ALDH1
- aldehyde dehydrogenase 2, mitochondrial
- mitochondrial aldehyde dehydrogenase
- ALDHI
- AHD-M1
Proteomics products related to ALDH2 Gene
Other products related to ALDH2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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