Androgen Receptor (Androgen Receptor, AR)
Short Description: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
More information related to gene Androgen Receptor.
More information related to gene Androgen Receptor.
Products related to Androgen Receptor Gene:
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OriGene rc215709l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Androgen Receptor (AR)
- NCBI Accession:
- NM_001011645,NP_001011645
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5338249
$976.14
Plus shipping costs $50.00
10 μg
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United States
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Synonyms and alternative names related to Androgen Receptor
- androgen receptor (AR)
- androgen receptor (Ar)
- androgen receptor (ar)
- AIS
- Andr
- AR
- AW320017
- DHTR
- HUMARA
- HYSP1
- KD
- NR3C4
- SBMA
- SMAX1
- TFM
- Tfm
Gene-IDs for different species
Protein level used designations for Androgen Receptor
- androgen nuclear receptor variant 2
- dihydrotestosterone receptor
- nuclear receptor subfamily 3 group C member 4
- testicular feminization
- androgen receptor (Testicular feminization), same as Tfm
- androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
- androgen receptor AR
- AR-A
- Ar beta
- androgen receptor
- prostate androgen receptor
Proteomics products related to Androgen Receptor Gene
Other products related to Androgen Receptor such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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