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APEX1 (Apurinic/Apyrimidinic Endonuclease 1, APEX1)

Short Description: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene\; all encode the same protein. [provided by RefSeq, Jul 2008].
More information related to gene APEX1.

Products related to APEX1 Gene:

80 results

OriGene rg213298 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Apurinic/Apyrimidinic Endonuclease 1 (APEX1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5376889
$484.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 10 Business Days
OriGene rg201208 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Apurinic/Apyrimidinic Endonuclease 1 (APEX1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5376887
$484.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 10 Business Days
OriGene rg201732 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Apurinic/Apyrimidinic Endonuclease 1 (APEX1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5376888
$484.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 10 Business Days
OriGene rg232466 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Apurinic/Apyrimidinic Endonuclease 1 (APEX1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5376890
$495.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene sr410362 RNAi APEX1 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Apurinic/Apyrimidinic Endonuclease 1
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3272831
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene sr500313 RNAi APEX1 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Apurinic/Apyrimidinic Endonuclease 1
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3350809
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene rc201732l2 ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
NCBI Accession:
NM_001641,NP_001632
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN5376897
$594.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene rc201208l2 ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
NCBI Accession:
NM_080648,NP_542379
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN5376896
$594.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene rc201208l1 ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
NCBI Accession:
NM_080648,NP_542379
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5376900
$594.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 10 Business Days
OriGene rc201732l1 ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
NCBI Accession:
NM_001641,NP_001632
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5376901
$594.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 10 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • ProteoGenix
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC
    • pCas-Guide
    • pDONR223
    • pCMV6-XL4
    • pCMV6-XL5
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to APEX1

  • apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1)
  • APEX nuclease (multifunctional DNA repair enzyme) 1 (apex1)
  • APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog (apex1.L)
  • DNA-(apurinic or apyrimidinic site) lyase (CNG03640)
  • DNA-(apurinic or apyrimidinic site) lyase (CNH01280)
  • DNA-(apurinic or apyrimidinic site) lyase (nth)
  • DNA-(apurinic or apyrimidinic site) lyase (Spirs_4119)
  • DNA-(apurinic or apyrimidinic site) lyase (Palpr_0103)
  • apurinic/apyrimidinic endodeoxyribonuclease 1 (Apex1)
  • apurinic/apyrimidinic endonuclease 1 (Apex1)
  • APE
  • APE1
  • APEN
  • APEX
  • Apex
  • apex1
  • apex1a
  • APX
  • BAP1
  • HAP1
  • hm:zehn1532
  • MGC76280
  • MGC78928
  • MGC79645
  • REF-1
  • Ref-1
  • REF1
  • wu:fc13d11
  • zgc:66204

Gene-IDs for different species

Protein level used designations for APEX1

  • DNA-(apurinic or apyrimidinic site) lyase
  • APEX nuclease 1
  • APEX nuclease (multifunctional DNA repair enzyme) 1
  • AP endonuclease class I
  • AP lyase
  • apurinic-apyrimidinic endonuclease 1
  • apurinic/apyrimidinic (abasic) endonuclease
  • deoxyribonuclease (apurinic or apyrimidinic)
  • protein REF-1
  • redox factor-1
  • AP endonuclease 1
  • APEN
  • apurinic/apyrimidinic endonuclease 1
  • apurinic/apyrimidinic endonuclease
  • zap1
  • Apurinic-apyrimidinic endonuclease 1
  • Redox factor-1
  • APEX nuclease
Other products related to APEX1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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