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APEX1 (Apurinic/Apyrimidinic Endonuclease 1, APEX1)

Short Description: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene\; all encode the same protein. [provided by RefSeq, Jul 2008].
More information related to gene APEX1.

Products related to APEX1 Gene:

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80 results

Rat APEX1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
NCBI Accession:
NM_024148
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5732964
$813.75
Plus shipping costs $50.00
1 μg
Shipping to: United States
Delivery in 11 to 22 Business Days
Details
Details
Human APEX1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5732962
$181.35
Plus shipping costs $50.00
1 μg
Shipping to: United States
Delivery in 11 to 22 Business Days
Details
Details
Human APEX1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5732961
$181.35
Plus shipping costs $50.00
1 μg
Shipping to: United States
Delivery in 11 to 22 Business Days
Details
Details
Mouse APEX1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
NCBI Accession:
NM_009687
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5732963
$813.75
Plus shipping costs $50.00
1 μg
Shipping to: United States
Delivery in 11 to 22 Business Days
Details
Details
Rat APEX1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
NCBI Accession:
NM_024148
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5219792
$857.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
Details
Details
Rat APEX1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
NCBI Accession:
NM_024148
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5219791
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
Details
Details
Mouse APEX1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
NCBI Accession:
NM_001039138
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5219790
$857.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
Details
Details
Mouse APEX1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
NCBI Accession:
NM_001039138
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5219789
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
Details
Details
Human APEX1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
NCBI Accession:
NM_001641
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5219788
$857.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
Details
Details
Human APEX1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
NCBI Accession:
NM_001641
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5219787
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • ProteoGenix
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC
    • pCas-Guide
    • pDONR223
    • pCMV6-XL4
    • pCMV6-XL5
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to APEX1

  • apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1)
  • APEX nuclease (multifunctional DNA repair enzyme) 1 (apex1)
  • APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog (apex1.L)
  • DNA-(apurinic or apyrimidinic site) lyase (CNG03640)
  • DNA-(apurinic or apyrimidinic site) lyase (CNH01280)
  • DNA-(apurinic or apyrimidinic site) lyase (nth)
  • DNA-(apurinic or apyrimidinic site) lyase (Spirs_4119)
  • DNA-(apurinic or apyrimidinic site) lyase (Palpr_0103)
  • apurinic/apyrimidinic endodeoxyribonuclease 1 (Apex1)
  • apurinic/apyrimidinic endonuclease 1 (Apex1)
  • APE
  • APE1
  • APEN
  • APEX
  • Apex
  • apex1
  • apex1a
  • APX
  • BAP1
  • HAP1
  • hm:zehn1532
  • MGC76280
  • MGC78928
  • MGC79645
  • REF-1
  • Ref-1
  • REF1
  • wu:fc13d11
  • zgc:66204

Gene-IDs for different species

Protein level used designations for APEX1

  • DNA-(apurinic or apyrimidinic site) lyase
  • APEX nuclease 1
  • APEX nuclease (multifunctional DNA repair enzyme) 1
  • AP endonuclease class I
  • AP lyase
  • apurinic-apyrimidinic endonuclease 1
  • apurinic/apyrimidinic (abasic) endonuclease
  • deoxyribonuclease (apurinic or apyrimidinic)
  • protein REF-1
  • redox factor-1
  • AP endonuclease 1
  • APEN
  • apurinic/apyrimidinic endonuclease 1
  • apurinic/apyrimidinic endonuclease
  • zap1
  • Apurinic-apyrimidinic endonuclease 1
  • Redox factor-1
  • APEX nuclease
Other products related to APEX1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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