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APEX1 (Apurinic/Apyrimidinic Endonuclease 1, APEX1)

Short Description: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene\; all encode the same protein. [provided by RefSeq, Jul 2008].
More information related to gene APEX1.

Products related to APEX1 Gene:

80 results

OriGene rc201208l1v ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN6393607
$841.50
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to: United States
Delivery in 21 to 26 Business Days
OriGene tr306647 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3772214
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 8 Business Days
OriGene tg306647 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3731535
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 8 Business Days
OriGene tr509102 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3541428
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tr710995 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3435884
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tl306647 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3751873
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tl710995 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3448275
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tl509102 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3521712
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene kn501392 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3246440
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 21 Business Days
OriGene kn201208 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3246439
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 10 to 12 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • ProteoGenix
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC
    • pCas-Guide
    • pDONR223
    • pCMV6-XL4
    • pCMV6-XL5
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to APEX1

  • apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1)
  • APEX nuclease (multifunctional DNA repair enzyme) 1 (apex1)
  • APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog (apex1.L)
  • DNA-(apurinic or apyrimidinic site) lyase (CNG03640)
  • DNA-(apurinic or apyrimidinic site) lyase (CNH01280)
  • DNA-(apurinic or apyrimidinic site) lyase (nth)
  • DNA-(apurinic or apyrimidinic site) lyase (Spirs_4119)
  • DNA-(apurinic or apyrimidinic site) lyase (Palpr_0103)
  • apurinic/apyrimidinic endodeoxyribonuclease 1 (Apex1)
  • apurinic/apyrimidinic endonuclease 1 (Apex1)
  • APE
  • APE1
  • APEN
  • APEX
  • Apex
  • apex1
  • apex1a
  • APX
  • BAP1
  • HAP1
  • hm:zehn1532
  • MGC76280
  • MGC78928
  • MGC79645
  • REF-1
  • Ref-1
  • REF1
  • wu:fc13d11
  • zgc:66204

Gene-IDs for different species

Protein level used designations for APEX1

  • DNA-(apurinic or apyrimidinic site) lyase
  • APEX nuclease 1
  • APEX nuclease (multifunctional DNA repair enzyme) 1
  • AP endonuclease class I
  • AP lyase
  • apurinic-apyrimidinic endonuclease 1
  • apurinic/apyrimidinic (abasic) endonuclease
  • deoxyribonuclease (apurinic or apyrimidinic)
  • protein REF-1
  • redox factor-1
  • AP endonuclease 1
  • APEN
  • apurinic/apyrimidinic endonuclease 1
  • apurinic/apyrimidinic endonuclease
  • zap1
  • Apurinic-apyrimidinic endonuclease 1
  • Redox factor-1
  • APEX nuclease
Other products related to APEX1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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