APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2, APEX2)
Short Description: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012].
More information related to gene APEX2.
More information related to gene APEX2.
Products related to APEX2 Gene:
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58 results
OriGene tr514741
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3547742
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene kn501393
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3246442
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn200320
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3246441
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr416495
RNAi
APEX2
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3264032
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr502559
RNAi
APEX2
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3352733
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl514741
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3527334
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl703980
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3512135
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene rn202845
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
- NCBI Accession:
- NM_001079892,NP_001073361
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3375991
$523.71
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc122813
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
- NCBI Accession:
- NM_014481,NP_055296
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3388237
$478.17
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene rc232544
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
- NCBI Accession:
- NM_001271748,NP_001258677
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5376947
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to APEX2
- apurinic/apyrimidinic endodeoxyribonuclease 2 (APEX2)
- apurinic/apyrimidinic endodeoxyribonuclease 2 (apex2)
- APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (apex2)
- apurinic/apyrimidinic endodeoxyribonuclease 2 L homeolog (apex2.L)
- APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2)
- apurinic/apyrimidinic endonuclease 2 (Apex2)
- apurinic/apyrimidinic endodeoxyribonuclease 2 (Apex2)
- APE2
- ape2
- APEXL2
- apexl2
- C430040P13Rik
- XTH2
- xth2
- zgc:55889
Gene-IDs for different species
Protein level used designations for APEX2
- AP endonuclease 2
- AP endonuclease XTH2
- DNA-(apurinic or apyrimidinic site) lyase 2
- apurinic/apyrimidinic endonuclease-like 2
- APEX nuclease 2
- apurinic-apyrimidinic endonuclease 2
- APEX nuclease (apurinic/apyrimidinic endonuclease) 2
- DNA-(apurinic or apyrimidinic site) lyase 2-like
Proteomics products related to APEX2 Gene
Other products related to APEX2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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