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APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2, APEX2)

Short Description: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012].
More information related to gene APEX2.

Products related to APEX2 Gene:

58 results :

Human APEX2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5732977
Datasheet
Catalog No. ABIN5732977
Type:
ORF
Application:
Cloning
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Species:
Human
Synonyms:
APEX2, apex2, apex2.L, Apex2
Insert length:
1557 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human APEX2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4472123
Datasheet
Catalog No. ABIN4472123
Type:
cDNA
Application:
Protein Expression
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Species:
Human
Synonyms:
APEX2, apex2, apex2.L, Apex2
Insert length:
1557 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat APEX2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_001079892
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5311202
Datasheet
Catalog No. ABIN5311202
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_001079892
Species:
Rat
Synonyms:
APEX2, apex2, apex2.L, Apex2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of RGD1565983
Format:
Viral Particles
Storage:
-80 °C
Mouse APEX2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_029943
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5104549
Datasheet
Catalog No. ABIN5104549
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_029943
Species:
Mouse
Synonyms:
APEX2, apex2, apex2.L, Apex2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Apex2
Format:
Viral Particles
Storage:
-80 °C
Human APEX2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_014481
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5104547
Datasheet
Catalog No. ABIN5104547
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_014481
Species:
Human
Synonyms:
APEX2, apex2, apex2.L, Apex2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of APEX2
Format:
Viral Particles
Storage:
-80 °C
Rat APEX2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_001079892
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5195586
Datasheet
Catalog No. ABIN5195586
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_001079892
Species:
Rat
Synonyms:
APEX2, apex2, apex2.L, Apex2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of RGD1565983
Format:
Viral Particles
Storage:
-80 °C
Human APEX2 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4826576
Datasheet
Catalog No. ABIN4826576
Type:
cDNA
Application:
Cloning
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Species:
Human
Synonyms:
APEX2, apex2, apex2.L, Apex2
Insert length:
1557 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human APEX2 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4758498
Datasheet
Catalog No. ABIN4758498
Type:
cDNA
Application:
Cloning
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Species:
Human
Synonyms:
APEX2, apex2, apex2.L, Apex2
Insert length:
1557 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human APEX2 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4433218
Datasheet
Catalog No. ABIN4433218
Type:
cDNA
Application:
Protein Expression
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Species:
Human
Synonyms:
APEX2, apex2, apex2.L, Apex2
Insert length:
1557 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human APEX2 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4697447
Datasheet
Catalog No. ABIN4697447
Type:
cDNA
Application:
Cloning
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Species:
Human
Synonyms:
APEX2, apex2, apex2.L, Apex2
Insert length:
1557 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL5
    • pDONR223
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to APEX2

  • apurinic/apyrimidinic endodeoxyribonuclease 2 (APEX2)
  • apurinic/apyrimidinic endodeoxyribonuclease 2 (apex2)
  • APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (apex2)
  • apurinic/apyrimidinic endodeoxyribonuclease 2 L homeolog (apex2.L)
  • APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2)
  • apurinic/apyrimidinic endonuclease 2 (Apex2)
  • apurinic/apyrimidinic endodeoxyribonuclease 2 (Apex2)
  • APE2
  • ape2
  • APEXL2
  • apexl2
  • C430040P13Rik
  • XTH2
  • xth2
  • zgc:55889

Gene-IDs for different species

Protein level used designations for APEX2

  • AP endonuclease 2
  • AP endonuclease XTH2
  • DNA-(apurinic or apyrimidinic site) lyase 2
  • apurinic/apyrimidinic endonuclease-like 2
  • APEX nuclease 2
  • apurinic-apyrimidinic endonuclease 2
  • APEX nuclease (apurinic/apyrimidinic endonuclease) 2
  • DNA-(apurinic or apyrimidinic site) lyase 2-like
Other products related to APEX2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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