ASAP2 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2, ASAP2)
Short Description: This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
More information related to gene ASAP2.
More information related to gene ASAP2.
Products related to ASAP2 Gene:
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45 results
OriGene rc226279
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2)
- NCBI Accession:
- NM_001135191,NP_001128663
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5400534
$958.32
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
OriGene rg226279
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5400532
$1,156.32
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
OriGene rg221783
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5400531
$781.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc221783
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2)
- NCBI Accession:
- NM_003887,NP_003878
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5400533
$867.24
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr305846
RNAi
ASAP2
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3345608
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to ASAP2
- ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (ASAP2)
- ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 L homeolog (asap2.L)
- ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b (asap1b)
- ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (asap2)
- ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (Asap2)
- 6530401G17Rik
- AMAP2
- asap2
- CENTB3
- DDEF2
- ddef2
- Ddef2
- Gm592
- Gm1523
- PAG3
- PAP
- Pap-alpha
- SHAG1
- si:dkey-37o8.2
Gene-IDs for different species
Protein level used designations for ASAP2
- development and differentiation enhancing factor 2
- development- and differentiation-enhancing factor 2
- ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
- asap1
- PYK2 C terminus-associated protein
- arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2
- centaurin, beta 3
- development and differentiation-enhancing factor 2
- paxillin-associated protein with ARF GAP activity 3
- pyk2 C-terminus-associated protein
Proteomics products related to ASAP2 Gene
Other products related to ASAP2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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