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ATF6 (Activating Transcription Factor 6, ATF6)

Short Description: This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011].
More information related to gene ATF6.

Products related to ATF6 Gene:

52 results

OriGene rc214278l1 ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Activating Transcription Factor 6 (ATF6)
NCBI Accession:
NM_007348,NP_031374
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5337113
$1,207.80
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
OriGene rc214278l2 ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Activating Transcription Factor 6 (ATF6)
NCBI Accession:
NM_007348,NP_031374
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN5337111
$1,207.80
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Mouse
    • Rat
    • Human
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-U6-sgRNA-PGK-Neo
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pRS
    • pCas-Guide
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Retroviral Vector
    • Bacterial Expression Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • ORF
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • SFFV Promoter
    • T7 Promoter
    • PGK Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to ATF6

  • activating transcription factor 6 (ATF6)
  • uncharacterized LOC412432 (LOC412432)
  • activating transcription factor 6 S homeolog (atf6.S)
  • cyclic AMP-dependent transcription factor ATF-6 alpha (LOC100122162)
  • activating transcription factor 6 (Atf6)
  • 9130025P16Rik
  • 9630036G24
  • AA789574
  • ATF-6-like
  • ATF6
  • Atf6
  • ATF6A
  • Atf6alpha
  • ESTM49
  • GB16435

Gene-IDs for different species

Protein level used designations for ATF6

  • activating transcription factor 6
  • cyclic AMP-dependent transcription factor ATF-6 alpha-like
  • cAMP-dependent transcription factor ATF-6 alpha
  • cyclic AMP-dependent transcription factor ATF-6 alpha
Other products related to ATF6 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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