ATF6 (Activating Transcription Factor 6, ATF6)
Short Description: This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011].
More information related to gene ATF6.
More information related to gene ATF6.
Products related to ATF6 Gene:
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OriGene rc214278l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Activating Transcription Factor 6 (ATF6)
- NCBI Accession:
- NM_007348,NP_031374
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5337111
$1,207.80
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5313192
$204.05
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 19 Business Days
Synonyms and alternative names related to ATF6
- activating transcription factor 6 (ATF6)
- uncharacterized LOC412432 (LOC412432)
- activating transcription factor 6 S homeolog (atf6.S)
- cyclic AMP-dependent transcription factor ATF-6 alpha (LOC100122162)
- activating transcription factor 6 (Atf6)
- 9130025P16Rik
- 9630036G24
- AA789574
- ATF-6-like
- ATF6
- Atf6
- ATF6A
- Atf6alpha
- ESTM49
- GB16435
Gene-IDs for different species
Protein level used designations for ATF6
- activating transcription factor 6
- cyclic AMP-dependent transcription factor ATF-6 alpha-like
- cAMP-dependent transcription factor ATF-6 alpha
- cyclic AMP-dependent transcription factor ATF-6 alpha
Proteomics products related to ATF6 Gene
Other products related to ATF6 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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