BPTF (Bromodomain PHD Finger Transcription Factor, BPTF)
Short Description: This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), identified as an 810 aa protein containing a DNA-binding domain and a zinc finger motif, suggested it might play a role in the regulation of transcription. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. The protein encoded by this gene is actually much larger than originally thought, and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation. The encoded protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex. In Drosophila, the NURF complex, which catalyzes nucleosome sliding on DNA and interacts with sequence-specific transcription factors, is necessary for the chromatin remodeling required for transcription. Two alternative transcripts encoding different isoforms have been described completely. [provided by RefSeq, Jul 2008].
More information related to gene BPTF.
More information related to gene BPTF.
Products related to BPTF Gene:
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42 results
OriGene rc223688
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Bromodomain PHD Finger Transcription Factor (BPTF)
- NCBI Accession:
- NM_004459,NP_004450
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5339774
$3,725.37
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 71 to 72 Business Days
OriGene sr301526
RNAi
BPTF
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Bromodomain PHD Finger Transcription Factor
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3341313
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to BPTF
- bromodomain PHD finger transcription factor (BPTF)
- bromodomain PHD finger transcription factor (Bptf)
- nucleosome-remodeling factor subunit NURF301 (LOC5576547)
- fetal alzheimer antigen, falz (CpipJ_CPIJ011285)
- bromodomain PHD finger transcription factor (bptf)
- 9430093H17Rik
- BPTF
- FAC1
- FALZ
- Falz
- NURF301
Gene-IDs for different species
Protein level used designations for BPTF
- bromodomain and PHD domain transcription factor
- bromodomain and PHD finger-containing transcription factor
- fetal Alz-50 clone 1 protein
- fetal Alz-50 reactive clone 1
- fetal Alzheimer antigen
- nucleosome remodeling factor, large subunit
- nucleosome-remodeling factor subunit BPTF
- fetal alzheimer antigen, falz
- bromodomain PHD finger transcription factor
- nucleosome-remodeling factor subunit BPTF-like
Proteomics products related to BPTF Gene
Other products related to BPTF such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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