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C4B (Complement Component C4b, C4b)

Short Description: This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. [provided by RefSeq, Jul 2008].
More information related to gene C4B.

Products related to C4B Gene:

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49 results

Human C4b CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
XM_001722806
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5131376
Catalog No. ABIN5131376
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
XM_001722806
Species:
Human
Synonyms:
C4B, C4A, c4, LOC462577, C4a, C4b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of C4B
Format:
Viral Particles
Storage:
-80 °C
Mouse C4b CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_009780
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5131378
Catalog No. ABIN5131378
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_009780
Species:
Mouse
Synonyms:
C4B, C4A, c4, LOC462577, C4a, C4b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of C4b
Format:
Viral Particles
Storage:
-80 °C
Rat C4b CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_031504
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5131382
Catalog No. ABIN5131382
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_031504
Species:
Rat
Synonyms:
C4B, C4A, c4, LOC462577, C4a, C4b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of C4b
Format:
Viral Particles
Storage:
-80 °C
Rat C4b CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_001002805
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5131380
Catalog No. ABIN5131380
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_001002805
Species:
Rat
Synonyms:
C4B, C4A, c4, LOC462577, C4a, C4b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of C4-2
Format:
Viral Particles
Storage:
-80 °C
Rat C4b CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_001002805
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5246831
Catalog No. ABIN5246831
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_001002805
Species:
Rat
Synonyms:
C4B, C4A, c4, LOC462577, C4a, C4b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of C4-2
Format:
Viral Particles
Storage:
-80 °C
Rat C4b CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_031504
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5246837
Catalog No. ABIN5246837
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_031504
Species:
Rat
Synonyms:
C4B, C4A, c4, LOC462577, C4a, C4b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of C4b
Format:
Viral Particles
Storage:
-80 °C
Mouse C4b CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_009780
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5246835
Catalog No. ABIN5246835
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_009780
Species:
Mouse
Synonyms:
C4B, C4A, c4, LOC462577, C4a, C4b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of C4b
Format:
Viral Particles
Storage:
-80 °C
Human C4b CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
XM_001722806
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5246833
Catalog No. ABIN5246833
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
XM_001722806
Species:
Human
Synonyms:
C4B, C4A, c4, LOC462577, C4a, C4b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of C4B
Format:
Viral Particles
Storage:
-80 °C
Human C4b CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
XM_001722806
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5131375
Catalog No. ABIN5131375
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
XM_001722806
Species:
Human
Synonyms:
C4B, C4A, c4, LOC462577, C4a, C4b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of C4B
Format:
Viral Particles
Storage:
-80 °C
Rat C4b CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_001002805
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5131379
Catalog No. ABIN5131379
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Complement Component C4b (C4b)
NCBI Accession:
NM_001002805
Species:
Rat
Synonyms:
C4B, C4A, c4, LOC462577, C4a, C4b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of C4-2
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Rat
    • Mouse
    • Human
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • Myc-DYKDDDDK Tag
    • GFP tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC-GFP
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • gRNA + Cas9
    • ORF
    • gRNA
    • shRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
    • T7 Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to C4B

  • complement C4B (Chido blood group) (C4B)
  • complement C4A (Rodgers blood group) (C4A)
  • complement component 4 (c4)
  • complement C4-B (LOC462577)
  • complement component 4B (Chido blood group) (C4B)
  • complement component 4A (Rodgers blood group) (C4a)
  • complement component 4B (Chido blood group) (C4b)
  • complement C4B (Chido blood group) (C4b)
  • C4
  • C4-2
  • C4A2
  • C4A3
  • C4A4
  • C4A6
  • C4AD
  • C4B
  • C4B1
  • C4B2
  • C4B3
  • C4B5
  • C4B12
  • C4BD
  • C4B_2
  • C4F
  • C4l
  • C4S
  • CH
  • CO4
  • CPAMD2
  • CPAMD3
  • DKFZP469I0332
  • RG
  • Slp
  • Ss
  • wu:fi14a03

Gene-IDs for different species

Protein level used designations for C4B

  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3
  • Chido form of C4
  • basic complement C4
  • complement C4-B
  • complement C4B1a
  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2
  • C4A anaphylatoxin
  • Rodgers form of C4
  • acidic C4
  • acidic complement C4
  • complement C4-A
  • complement component 4A
  • complement component 4B
  • complement component 4B (Chido blood group)
  • sex-limited protein
  • complement component 4 (within H-2S)
  • complement component 4B (Childo blood group)
  • complement C4-like protein
  • complement component 4, gene 2
Other products related to C4B such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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