CADM1 (Cell Adhesion Molecule 1, CADM1)
Short Description: Mediates homophilic cell-cell adhesion in a Ca(2+)- independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. May act as a synaptic cell adhesion molecule that drives synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
More information related to gene CADM1.
More information related to gene CADM1.
Products related to CADM1 Gene:
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83 results
OriGene sr308445
RNAi
CADM1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Cell Adhesion Molecule 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3284484
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5320312
$215.19
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 19 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5325414
$215.19
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 19 Business Days
Synonyms and alternative names related to CADM1
- cell adhesion molecule 1 (CADM1)
- cell adhesion molecule 1 L homeolog (cadm1.L)
- cell adhesion molecule 1 (Cadm1)
- 2900073G06Rik
- 3100001I08Rik
- AI987920
- BL2
- bl2
- Bl2
- IGSF4
- igsf4
- Igsf4
- IGSF4A
- igsf4a
- Igsf4a
- Necl-2
- necl-2
- NECL2
- necl2
- Necl2
- RA175
- ra175
- RA175A
- RA175B
- RA175C
- RA175N
- sgIGSF
- sgigsf
- SgIGSF
- ST17
- st17
- sTSLC-1
- stslc-1
- SYNCAM
- syncam
- SynCam
- synCAM1
- syncam1
- SynCAM1
- TSLC1
- tslc1
- Tslc1
- xnecl2
Gene-IDs for different species
Protein level used designations for CADM1
- TSLC-1
- TSLC1/Nectin-like 2/IGSF4
- immunoglobulin superfamily member 4
- immunoglobulin superfamily, member 4
- immunoglobulin superfamily, member 4D variant 1
- immunoglobulin superfamily, member 4D variant 2
- nectin-like 2
- nectin-like protein 2
- spermatogenic immunoglobulin superfamily
- synaptic cell adhesion molecule
- truncated CADM1 protein
- tumor suppressor in lung cancer 1
- cell adhesion molecule 1
- NECL-2
- cell adhesion molecule 1 transcript variant 8abc
- immunoglobulin superfamily member 4A
- immunosuperfamily protein Bl2
- immunoglobulin superfamily, member 4A
- secretory isoform of TSLC1
- tumor suppressor in lung cell-1
Proteomics products related to CADM1 Gene
Other products related to CADM1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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