CASC5 (Cancer Susceptibility Candidate 5, CASC5)
Short Description: The protein encoded by this gene is a component of the multiprotein assembly that is required for creation of kinetochore-microtubule attachments and chromosome segregation. The encoded protein functions as a scaffold for proteins that influence the spindle assembly checkpoint during the eukaryotic cell cycle and it interacts with at least five different kinetochore proteins and two checkpoint kinases. In adults, this gene is predominantly expressed in normal testes, various cancer cell lines and primary tumors from other tissues and is ubiquitously expressed in fetal tissues. This gene was originally identified as a fusion partner with the mixed-lineage leukemia (MLL) gene in t(11\;15)(q23\;q14). Mutations in this gene cause autosomal recessive primary microcephaly-4 (MCPH4). Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jan 2013].
More information related to gene CASC5.
More information related to gene CASC5.
Products related to CASC5 Gene:
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49 results
OriGene mc225178
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Cancer Susceptibility Candidate 5 (CASC5)
- NCBI Accession:
- NM_029617,NP_083893
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3294765
$1,904.76
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 61 to 62 Business Days
OriGene rn217739
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Cancer Susceptibility Candidate 5 (CASC5)
- NCBI Accession:
- NM_001170594,NP_001164065
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3294766
$1,900.80
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 41 to 42 Business Days
OriGene sr423063
RNAi
CASC5
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Cancer Susceptibility Candidate 5
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3349913
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene rc217375
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cancer Susceptibility Candidate 5 (CASC5)
- NCBI Accession:
- NM_144508,NP_653091
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5340801
$2,080.98
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 61 to 62 Business Days
OriGene rc217605
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cancer Susceptibility Candidate 5 (CASC5)
- NCBI Accession:
- NM_170589,NP_733468
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5340802
$1,913.67
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rg217375
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cancer Susceptibility Candidate 5 (CASC5)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5340799
$2,278.98
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 61 to 62 Business Days
OriGene rr217739
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cancer Susceptibility Candidate 5 (CASC5)
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5340803
$1,899.81
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 41 to 42 Business Days
OriGene rg217605
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cancer Susceptibility Candidate 5 (CASC5)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5340800
$2,309.67
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr311333
RNAi
CASC5
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Cancer Susceptibility Candidate 5
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3287364
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to CASC5
- kinetochore scaffold 1 (KNL1)
- kinetochore scaffold 1 (Knl1)
- Kinetochore null protein 1 (knl-1)
- 2310043D08Rik
- 5730505K17Rik
- AF15Q14
- CT29
- D40
- hKNL-1
- hSpc105
- KNL1
- PPP1R55
- Rad51
- Spc7
Gene-IDs for different species
Protein level used designations for CASC5
- cancer susceptibility candidate 5
- ALL1-fused gene from chromosome 15q14 protein
- blinkin, bub-linking kinetochore protein
- cancer susceptibility candidate gene 5 protein
- cancer/testis antigen 29
- kinetochore null 1 homolog
- kinetochore-null protein 1
- protein CASC5
- protein phosphatase 1, regulatory subunit 55
- RAD51 homolog
Proteomics products related to CASC5 Gene
Other products related to CASC5 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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