CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase, CASP5)
Short Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc\\/Max\\/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein\\\\; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010].
More information related to gene CASP5.
More information related to gene CASP5.
Products related to CASP5 Gene:
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42 results
OriGene rc210421
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5)
- NCBI Accession:
- NM_004347,NP_004338
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5431720
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr300593
RNAi
CASP5
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Caspase 5, Apoptosis-Related Cysteine Peptidase
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3340387
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to CASP5
- caspase 5 (CASP5)
- caspase-5 (LOC100437308)
- CASP5
- ICE(rel)III
- ICEREL-III
- ICH-3
Gene-IDs for different species
Protein level used designations for CASP5
- CASP-5
- ICE(rel)-III
- TY protease
- caspase 5, apoptosis-related cysteine protease
- caspase-5
- protease ICH-3
- protease TY
- caspase 5
- caspase 5, apoptosis-related cysteine peptidase
- caspase-5-like
Proteomics products related to CASP5 Gene
Other products related to CASP5 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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