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Caspase 1 (Caspase 1, CASP1)

Short Description: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012].
More information related to gene Caspase 1.

Products related to Caspase 1 Gene:

86 results

OriGene kn409125 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Caspase 1 (CASP1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3249270
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene mc207999 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Caspase 1 (CASP1)
NCBI Accession:
NP_033937
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3294775
$679.14
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene rn210506 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Caspase 1 (CASP1)
NCBI Accession:
NM_012762,NP_036894
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3294776
$724.68
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sr510219 RNAi CASP1 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Caspase 1
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3359296
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tf709383 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Caspase 1 (CASP1)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3489662
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sc309463 cDNA PExp Mammalian Expression Vector pCMV6-AC Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Caspase 1 (CASP1)
NCBI Accession:
NM_033294,NP_150636
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient, Stable
Catalog No. ABIN3319662
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sc321044 cDNA PExp Mammalian Expression Vector pCMV6-AC Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Caspase 1 (CASP1)
NCBI Accession:
NM_033293,NP_150635
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient, Stable
Catalog No. ABIN3317347
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sc309462 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Caspase 1 (CASP1)
NCBI Accession:
NM_033293,NP_150635
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3321873
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sc310462 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Caspase 1 (CASP1)
NCBI Accession:
NM_001223,NP_001214
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3321874
$679.14
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sc308821 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Pubmed 1
Type:
cDNA
Application:
Protein Expression
Gene:
Caspase 1 (CASP1)
NCBI Accession:
NM_033292,NP_150634
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3388736
$679.14
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC
    • pCMV6-XL5
    • pCas-Guide
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to Caspase 1

  • caspase 1 (CASP1)
  • caspase 1 (Casp1)
  • caspase 1, apoptosis-related cysteine peptidase (CASP1)
  • caspase 4, apoptosis-related cysteine peptidase (CASP4)
  • Death caspase-1 (Dcp-1)
  • caspase-1 (Caspase1)
  • caspase (LOC5564196)
  • caspase recruitment domain-containing protein 16 (LOC451519)
  • caspase-1 (CASP1)
  • caspase 4 (CASP4)
  • CASP1
  • ccp1
  • CG5370
  • DCP-1
  • dcp-1
  • DCP1
  • Dcp1
  • dcp1
  • Dmel\\CG5370
  • ICE
  • Ice
  • IL1BC
  • Il1bc
  • l(2)01862
  • l(2)02132
  • P45

Gene-IDs for different species

Protein level used designations for Caspase 1

  • CASP1 nirs variant 1
  • IL-1 beta-converting enzyme
  • IL1B-convertase
  • caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
  • caspase-1
  • interleukin 1, beta, convertase
  • interleukin 1-B converting enzyme
  • CASP-1
  • IL-1B converting enzyme
  • IL-1BC
  • interleukin 1 beta-converting enzyme
  • interleukin-1 beta convertase
  • interleukin-1 beta-converting enzyme
  • p45
  • Interleukin 1beta converting enzyme
  • caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
  • ICE
  • interleukin-1 beta converting enzyme
  • caspase-1/caspase-4 hybrid
  • CG5370-PA
  • Dcp-1-PA
  • caspase
  • caspase 1
  • death caspase-1
Other products related to Caspase 1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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