Short Description: The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene. [provided by RefSeq, Jul 2008]. More information related to gene Cathepsin E.
Synonyms and alternative names related to Cathepsin E
cathepsin E (CTSE)
cathepsin E (Ctse)
cathepsin E (TP03_0056)
cathepsin E (Smp_184930)
cathepsin E (ctse)
cathepsin E L homeolog (ctse.L)
cathepsin E S homeolog (ctse.S)
A430072O03Rik
C920004C08Rik
CATE
CatE
cate
CE
ce1
CE1
ce1-A
ce2
CE2
ce2-A
CEA
CEB
CTSE
ctse
Ctsea
Gene-IDs for different species
Protein level used designations for Cathepsin E
erythrocyte membrane aspartic proteinase
slow-moving proteinase
cathepsin E
procathepsin E
cathepsin E-A
cathepsin E1
cathepsin E-B
cathepsin E2
Proteomics products related to Cathepsin E Gene
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