Cathepsin F (Cathepsin F, CTSF)
Short Description: Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W. [provided by RefSeq, Jul 2008].
More information related to gene Cathepsin F.
More information related to gene Cathepsin F.
Products related to Cathepsin F Gene:
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51 results
OriGene rc204047
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cathepsin F (CTSF)
- NCBI Accession:
- NM_003793,NP_003784
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5342743
$502.70
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10 μg
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Synonyms and alternative names related to Cathepsin F
- cathepsin F (CTSF)
- cathepsin F (ctsf)
- cathepsin F (Ctsf)
- cathepsin W (ctsw)
- cathepsin F (Tsp_02382)
- ACYPI000376
- AI481912
- catf
- CATSF
- cb420
- CLN13
- CTSF
- Ctsf
- LOC100101596
- MGC140519
- sb:cb420
- zgc:153093
Gene-IDs for different species
Protein level used designations for Cathepsin F
- cathepsin F
- hypothetical protein LOC100158959
- Cathepsin F
- cathepsin F-like
Proteomics products related to Cathepsin F Gene
Other products related to Cathepsin F such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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