CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2, CBFA2T2)
Short Description: In acute myeloid leukemia, especially in the M2 subtype, the t(8\;21)(q22\;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. [provided by RefSeq, Jul 2008].
More information related to gene CBFA2T2.
More information related to gene CBFA2T2.
Products related to CBFA2T2 Gene:
Recommended next Filters:
69 results
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
- NCBI Accession:
- NM_005093
- Gene ID:
- 9139 (Human, CBFA2T2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4931959
$439.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
OriGene rg202013
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5377844
$484.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rg222716
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5377846
$754.38
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc218940
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
- NCBI Accession:
- NM_001032999,NP_001028171
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5377848
$286.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rr216974
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5377850
$601.92
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rg218940
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5377845
$746.46
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc202013
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
- NCBI Accession:
- NM_001039709,NP_001034798
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5377847
$566.28
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc222716
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
- NCBI Accession:
- NM_005093,NP_005084
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5377849
$286.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr306045
RNAi
CBFA2T2
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3345807
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to CBFA2T2
- CBFA2/RUNX1 translocation partner 2 (Cbfa2t2)
- CBFA2/RUNX1 translocation partner 2 (CBFA2T2)
- core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) (Cbfa2t2)
- CBFA2/RUNX1 translocation partner 2 L homeolog (cbfa2t2.L)
- A430091M07
- C330013D05Rik
- cbfa2t2-a
- Cbfa2t2h
- EHT
- MTGR1
- p85
- XETOR
- ZMYND3
Gene-IDs for different species
Protein level used designations for CBFA2T2
- translocated to, 2
- myeloid translocation gene-related protein 1
- protein CBFA2T2
- CBFA2T2 identified gene homolog
- MTG8-like protein
- MTG8-related protein 1
- core-binding factor runt domain alpha subunit 2 translocated to 2 homolog
- core-binding factor, runt domain, alpha subunit 2, translocated to, 2 homolog
- ETO homolog on chromosome 20
- ETO homologous on chromosome 20
- myeloid translocation-related protein 1
- a subunit 2; translocated to, 2
- expressed during neurogenesis
Proteomics products related to CBFA2T2 Gene
Other products related to CBFA2T2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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