Short Description: Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta\\\\; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008]. More information related to gene CD235b/GYPB.
Synonyms and alternative names related to CD235b/GYPB
glycophorin B (MNS blood group) (GYPB)
CD235b
GPB
GPB.NY
GpMiIII
GYPHe.NY
HGpMiIII
HGpMiVI
HGpMiX
MNS
PAS-3
SS
Gene-IDs for different species
Protein level used designations for CD235b/GYPB
SS-active sialoglycoprotein
Ss blood group
glycophorin HeP2
glycophorin MiIII
glycophorin MiVI
glycophorin MiX
glycophorin-B
sialoglycoprotein delta
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