CD59 (CD59, CD59)
Short Description: This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].
More information related to gene CD59.
More information related to gene CD59.
Products related to CD59 Gene:
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ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5315242
$204.05
Plus shipping costs $50.00
2 μg
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Synonyms and alternative names related to CD59
- CD59 molecule (CD59 blood group) (CD59)
- CD59 molecule (Cd59)
- CD59 molecule (CD59)
- 1F5
- 16.3A5
- Cd59a
- Cd59b
- EJ16
- EJ30
- EL32
- G344
- HRF-20
- HRF20
- MAC-IP
- MACIF
- MACIP
- MEM43
- MIC11
- MIN1
- MIN2
- MIN3
- MIRL
- MSK21
- p18-20
Gene-IDs for different species
Protein level used designations for CD59
- 1F5 antigen
- 20 kDa homologous restriction factor
- CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)
- CD59 glycoprotein
- Ly-6-like protein
- MEM43 antigen
- T cell-activating protein
- human leukocyte antigen MIC11
- lymphocytic antigen CD59/MEM43
- membrane attack complex (MAC) inhibition factor
- membrane attack complex inhibition factor
- membrane inhibitor of reactive lysis
- protectin
- surface anitgen recognized by monoclonal antibody 16.3A5
- CD59 antigen
- CD59b moleucle, complement regulatory protein
- Cb59b molecule
- MAC-inhibitory protein
- MAC-IP
- MACIF
- CD59 homolog
- CD59 molecule, complement regulatory protein
Proteomics products related to CD59 Gene
Other products related to CD59 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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