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CDK4 (Cyclin-Dependent Kinase 4, CDK4)

Short Description: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008].
More information related to gene CDK4.

Products related to CDK4 Gene:

63 results

OriGene mc207247 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
NCBI Accession:
NM_009870,NP_034000
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3295781
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene tr711993 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3436880
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sr510569 RNAi CDK4 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Cyclin-Dependent Kinase 4
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3359601
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sc323451 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
NCBI Accession:
NM_000075,NP_000066
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3388895
$445.50
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sc323460 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
NCBI Accession:
NM_000075,NP_000066
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3388896
$445.50
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sc323699 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
NCBI Accession:
NM_000075,NP_000066
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3388897
$445.50
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sc112998 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Pubmed 1
Type:
cDNA
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
NCBI Accession:
NM_000075,NP_000066
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3383212
$445.50
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene rg201156 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
NCBI Accession:
NM_000075,NP_000066
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5378089
$484.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene rc201156 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
NCBI Accession:
NM_000075,NP_000066
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5378090
$445.50
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
OriGene rr210857 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
NCBI Accession:
NM_053593,NP_446045
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5378091
$475.20
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pCMV6-XL5
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA
    • gRNA + Cas9
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to CDK4

  • cyclin-dependent kinase 4 (cdk4)
  • cyclin dependent kinase 4 (CDK4)
  • cyclin-dependent kinase 4 (Cdk4)
  • cyclin dependent kinase 4 (Cdk4)
  • Cyclin-dependent kinase 4 (Cdk4)
  • cyclin-dependent kinase 4 L homeolog (cdk4.L)
  • 8-6
  • cdk
  • CDK4
  • cdk4
  • CDK4/6
  • Cdk4/6
  • cdk4/6
  • CG5072
  • CMM3
  • Crk3
  • dCdk4
  • DmCdk4
  • Dmel\\CG5072
  • l(2)05428
  • l(2)0671
  • l(2)k06503
  • l(2)s4639
  • l(2)sh0671
  • Pk53C
  • Pk?7
  • PSK-J3
  • xcdk4
  • zgc:153726

Gene-IDs for different species

Protein level used designations for CDK4

  • cell division protein kinase 4
  • PSK-J3
  • cyclin dependent kinase 4
  • p34/cdk4
  • serine/threonine kinase
  • Cell division protein kinase 4
  • CG5072-PA
  • CG5072-PB
  • CG5072-PC
  • Cdk4-PA
  • Cdk4-PB
  • Cdk4-PC
  • Cyclin-dependent kinase 4/6
  • cyclin-dependent kinase 4
  • protein kinase-like 53C
Other products related to CDK4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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