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CDK4 (Cyclin-Dependent Kinase 4, CDK4)

Short Description: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008].
More information related to gene CDK4.

Products related to CDK4 Gene:

63 results

cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
NCBI Accession:
NM_009870
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4495716
$603.36
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 32 Business Days
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4699647
$805.29
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 32 Business Days
ORF Clon Gateway Cloning Vector pDONR223 Spectinomycin unconjugated
Type:
ORF
Application:
Cloning
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
Gene ID:
1019 (Human, CDK4)
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin
Catalog No. ABIN5316241
$223.79
Plus shipping costs $50.00
2 μg
Shipping to: United States
Delivery in 15 to 19 Business Days
OriGene rc201156l1v ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN6393513
$990.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to: United States
Delivery in 21 to 27 Business Days
OriGene rc201156l2v ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN6393514
$990.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to: United States
Delivery in 21 to 27 Business Days
OriGene tl320293 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3764424
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tf320293 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3723748
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene tg511864 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3693869
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tf511864 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3674171
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tg320293 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Pubmed 1
Type:
shRNA
Application:
RNA Interference
Gene:
Cyclin-Dependent Kinase 4 (CDK4)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3744086
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pCMV6-XL5
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA
    • gRNA + Cas9
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to CDK4

  • cyclin-dependent kinase 4 (cdk4)
  • cyclin dependent kinase 4 (CDK4)
  • cyclin-dependent kinase 4 (Cdk4)
  • cyclin dependent kinase 4 (Cdk4)
  • Cyclin-dependent kinase 4 (Cdk4)
  • cyclin-dependent kinase 4 L homeolog (cdk4.L)
  • 8-6
  • cdk
  • CDK4
  • cdk4
  • CDK4/6
  • Cdk4/6
  • cdk4/6
  • CG5072
  • CMM3
  • Crk3
  • dCdk4
  • DmCdk4
  • Dmel\\CG5072
  • l(2)05428
  • l(2)0671
  • l(2)k06503
  • l(2)s4639
  • l(2)sh0671
  • Pk53C
  • Pk?7
  • PSK-J3
  • xcdk4
  • zgc:153726

Gene-IDs for different species

Protein level used designations for CDK4

  • cell division protein kinase 4
  • PSK-J3
  • cyclin dependent kinase 4
  • p34/cdk4
  • serine/threonine kinase
  • Cell division protein kinase 4
  • CG5072-PA
  • CG5072-PB
  • CG5072-PC
  • Cdk4-PA
  • Cdk4-PB
  • Cdk4-PC
  • Cyclin-dependent kinase 4/6
  • cyclin-dependent kinase 4
  • protein kinase-like 53C
Other products related to CDK4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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