CEP57 (Centrosomal Protein 57kDa, CEP57)
Short Description: This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
More information related to gene CEP57.
More information related to gene CEP57.
Products related to CEP57 Gene:
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62 results
OriGene rr210950
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Centrosomal Protein 57kDa (CEP57)
- NCBI Accession:
- NM_001108124,NP_001101594
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5372247
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr306471
RNAi
CEP57
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Centrosomal Protein 57kDa
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3346231
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to CEP57
- centrosomal protein 57 (CEP57)
- centrosomal protein 57kDa-like 1 (cep57l1)
- centrosomal protein 57 (Cep57)
- 3110002L15RIK
- 3110002l15rik
- 3110002L15Rik
- 4921510P06Rik
- 4931428M20Rik
- AI467480
- c6orf182
- CEP57
- cep57r
- mKIAA0092
- MVA2
- PIG8
- RGD1309884
- Tsp57
- TSP57
- xCep57
Gene-IDs for different species
Protein level used designations for CEP57
- translokin
- centrosomal protein 57kDa
- cep57-related protein
- Cep57-related protein
- Centrosomal protein of 57 kDa
- centrosomal protein of 57 kDa-like
- centrosomal protein of 57 kDa
- testis-specific protein 57
- FGF2-interacting protein
- proliferation-inducing protein 8
Proteomics products related to CEP57 Gene
Other products related to CEP57 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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