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CHFR (Checkpoint with Forkhead and Ring Finger Domains, CHFR)

Short Description: E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating ubc13-mms2 (ube2n-ube2v2) heterodimer. Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress (By similarity).
More information related to gene CHFR.

Products related to CHFR Gene:

80 results

OriGene rc228525 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Checkpoint with Forkhead and Ring Finger Domains (CHFR)
NCBI Accession:
NM_001161345,NP_001154817
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5378033
$286.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
OriGene rc228526 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Checkpoint with Forkhead and Ring Finger Domains (CHFR)
NCBI Accession:
NM_001161344,NP_001154816
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5378034
$611.82
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
OriGene rr210736 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Checkpoint with Forkhead and Ring Finger Domains (CHFR)
NCBI Accession:
NM_001009258,NP_001009258
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5378036
$672.21
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene rc228465l1 ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Checkpoint with Forkhead and Ring Finger Domains (CHFR)
NCBI Accession:
NM_001161347,NP_001154819
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5378044
$823.68
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Checkpoint with Forkhead and Ring Finger Domains (CHFR)
NCBI Accession:
NM_001161344
Gene ID:
55743 (Human, CHFR)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4931445
$439.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Checkpoint with Forkhead and Ring Finger Domains (CHFR)
NCBI Accession:
NM_001161347
Gene ID:
55743 (Human, CHFR)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4931448
$439.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Checkpoint with Forkhead and Ring Finger Domains (CHFR)
NCBI Accession:
NM_001161346
Gene ID:
55743 (Human, CHFR)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4931446
$439.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Checkpoint with Forkhead and Ring Finger Domains (CHFR)
NCBI Accession:
NM_018223
Gene ID:
55743 (Human, CHFR)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4931447
$99.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Checkpoint with Forkhead and Ring Finger Domains (CHFR)
NCBI Accession:
NM_001161345
Gene ID:
55743 (Human, CHFR)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4931449
$439.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
OriGene sr310903 RNAi CHFR Species: Human HPLC purified
Application:
RNA Interference
Gene:
Checkpoint with Forkhead and Ring Finger Domains
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3286935
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-XL5
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • Enhanced CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to CHFR

  • checkpoint with forkhead and ring finger domains (CHFR)
  • checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase (chfr)
  • checkpoint with forkhead and ring finger domains (Chfr)
  • checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase L homeolog (chfr.L)
  • 5730484M20Rik
  • C230082M18
  • CHFR
  • fc43f10
  • RNF116
  • rnf116
  • RNF196
  • rnf196
  • si:dkey-69h6.7
  • wu:fc43f10

Gene-IDs for different species

Protein level used designations for CHFR

  • E3 ubiquitin-protein ligase CHFR
  • RING finger protein 196
  • checkpoint with forkhead and RING finger domains protein
  • checkpoint with forkhead and ring finger domains
  • Checkpoint with forkhead and RING finger domains protein
  • e3 ubiquitin-protein ligase CHFR-like
Other products related to CHFR such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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