CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal), CHRNA7)
Short Description: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia. An evolutionarily recent partial duplication event in this region results in a hybrid containing sequence from this gene and a novel FAM7A gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].
More information related to gene CHRNA7.
More information related to gene CHRNA7.
Products related to CHRNA7 Gene:
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60 results
OriGene sc124074
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL4
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7)
- NCBI Accession:
- NM_000746,NP_000737
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL4
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3381037
$694.98
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7)
- NCBI Accession:
- NM_001190455
- Gene ID:
- 1139 (Human, CHRNA7)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4931394
$449.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7)
- NCBI Accession:
- NM_000746
- Gene ID:
- 1139 (Human, CHRNA7)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4940592
$419.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene rg221382
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5424456
$891.99
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rg231298
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5424457
$484.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc221382l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7)
- NCBI Accession:
- NM_000746,NP_000737
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5424461
$990.99
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc221382l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7)
- NCBI Accession:
- NM_000746,NP_000737
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5424464
$990.99
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc221382
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7)
- NCBI Accession:
- NM_000746,NP_000737
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5424458
$693.99
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc231298
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7)
- NCBI Accession:
- NM_001190455,NP_001177384
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5424459
$286.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rr202164
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7)
- NCBI Accession:
- NM_012832,NP_036964
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5424460
$508.86
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to CHRNA7
- cholinergic receptor nicotinic alpha 7 subunit (CHRNA7)
- neuronal acetylcholine receptor subunit alpha-7 (LOC100374356)
- cholinergic receptor, nicotinic, alpha 7 (neuronal) (chrna7)
- cholinergic receptor, nicotinic, alpha polypeptide 7 (Chrna7)
- cholinergic receptor nicotinic alpha 7 subunit (Chrna7)
- cholinergic receptor, nicotinic, alpha 7 (CHRNA7)
- neuronal acetylcholine receptor subunit alpha-7 (LOC100060521)
- Acra7
- alpha7
- BTX
- CHRNA7
- CHRNA7-2
- dZ70B1.1
- NACHRA7
- nAChRa7
- NARAD
Gene-IDs for different species
Protein level used designations for CHRNA7
- a7 nicotinic acetylcholine receptor
- alpha 7 neuronal nicotinic acetylcholine receptor
- alpha-7 nicotinic cholinergic receptor subunit
- cholinergic receptor, nicotinic, alpha polypeptide 7
- neuronal acetylcholine receptor protein, alpha-7 chain
- neuronal acetylcholine receptor subunit alpha-7
- cholinergic receptor, nicotinic, alpha 7
- neuronal acetylcholine receptor subunit alpha-7-like
- acetylcholine receptor alpha 7 neural
- alpha7 nicotinic receptor
- alpha7-nAChR
- C holinergic receptor nicotinic alpha polypeptide 7 (neuronal nicotinic acetycholine receptor alpha 7) (bungarotoxin alpha)
- C holinergic receptor, nicotinic, alpha polypeptide 7 (neuronal nicotinic acetycholine receptor alpha 7) (bungarotoxin alpha)
- bungarotoxin alpha
- neuronal nicotinic acetycholine receptor alpha 7
- nicotinic receptor alpha 7 subunit
- cholinergic receptor nicotinic alpha 7
- alpha 7 nicotinic acetylcholine receptor
- nicotinic acetylcholine receptor alpha7
- CHRNA7-FAM7A fusion protein
- cholinergic receptor, nicotinic, alpha 7 (neuronal)
Proteomics products related to CHRNA7 Gene
Other products related to CHRNA7 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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