CIITA (Class II, Major Histocompatibility Complex, Transactivator, CIITA)
Short Description: This gene encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. The protein is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the 'master control factor' for the expression of these genes. The protein also binds GTP and uses GTP binding to facilitate its own transport into the nucleus. Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion. Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction. [provided by RefSeq, Jul 2008].
More information related to gene CIITA.
More information related to gene CIITA.
Products related to CIITA Gene:
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OriGene rc222253l2v
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Class II, Major Histocompatibility Complex, Transactivator (CIITA)
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN6424071
$2,004.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to:
United States
Delivery in 21 to 27 Business Days
OriGene rc222253l1v
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Class II, Major Histocompatibility Complex, Transactivator (CIITA)
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN6424070
$2,004.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to:
United States
Delivery in 21 to 27 Business Days
Synonyms and alternative names related to CIITA
- class II, major histocompatibility complex, transactivator (CIITA)
- class II major histocompatibility complex transactivator (CIITA)
- MHC class II transactivator (LOC710761)
- class II, major histocompatibility complex, transactivator (ciita)
- MHC class II transactivator (LOC100443575)
- class II transactivator (Ciita)
- MHC class II transactivator (LOC100736732)
- class II, major histocompatibility complex, transactivator (Ciita)
- C2ta
- C2TA
- CIITA
- CIITAIV
- EG669998
- Gm9475
- MHC2TA
- Mhc2ta
- NLRA
Gene-IDs for different species
Protein level used designations for CIITA
- class II, major histocompatibility complex, transactivator
- class II transactivator-like
- class II transactivator
- MHC class II transactivator-like
- MHC class II transactivator
- MHC class II transactivator type III
- NLR family, acid domain containing
- nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing
- MHC class II transactivator type IV
Proteomics products related to CIITA Gene
Other products related to CIITA such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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