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CIITA (Class II, Major Histocompatibility Complex, Transactivator, CIITA)

Short Description: This gene encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. The protein is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the 'master control factor' for the expression of these genes. The protein also binds GTP and uses GTP binding to facilitate its own transport into the nucleus. Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion. Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction. [provided by RefSeq, Jul 2008].
More information related to gene CIITA.

Products related to CIITA Gene:

72 results :

Mouse CIITA cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_001243760
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4496082
Datasheet
Catalog No. ABIN4496082
Type:
cDNA
Application:
Protein Expression
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_001243760
Species:
Mouse
Synonyms:
CIITA, LOC710761, ciita, LOC100443575, Ciita, LOC100736732
Insert length:
3465 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat CIITA CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_053529
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5086468
Datasheet
Catalog No. ABIN5086468
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_053529
Species:
Rat
Synonyms:
CIITA, LOC710761, ciita, LOC100443575, Ciita, LOC100736732
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ciita
Format:
Viral Particles
Storage:
-80 °C
Human CIITA CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_000246
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5086464
Datasheet
Catalog No. ABIN5086464
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_000246
Species:
Human
Synonyms:
CIITA, LOC710761, ciita, LOC100443575, Ciita, LOC100736732
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CIITA
Format:
Viral Particles
Storage:
-80 °C
Mouse CIITA CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_001243760
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5086466
Datasheet
Catalog No. ABIN5086466
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_001243760
Species:
Mouse
Synonyms:
CIITA, LOC710761, ciita, LOC100443575, Ciita, LOC100736732
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ciita
Format:
Viral Particles
Storage:
-80 °C
Mouse CIITA ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_001243760
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5722519
Datasheet
Catalog No. ABIN5722519
Type:
ORF
Application:
Cloning
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_001243760
Species:
Mouse
Synonyms:
CIITA, LOC710761, ciita, LOC100443575, Ciita, LOC100736732
Insert length:
3465 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse CIITA ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_007575
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5722520
Datasheet
Catalog No. ABIN5722520
Type:
ORF
Application:
Cloning
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_007575
Species:
Mouse
Synonyms:
CIITA, LOC710761, ciita, LOC100443575, Ciita, LOC100736732
Insert length:
3237 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat CIITA ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_053529
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5722522
Datasheet
Catalog No. ABIN5722522
Type:
ORF
Application:
Cloning
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_053529
Species:
Rat
Synonyms:
CIITA, LOC710761, ciita, LOC100443575, Ciita, LOC100736732
Insert length:
3462 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse CIITA cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_001243760
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4849032
Datasheet
Catalog No. ABIN4849032
Type:
cDNA
Application:
Cloning
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_001243760
Species:
Mouse
Synonyms:
CIITA, LOC710761, ciita, LOC100443575, Ciita, LOC100736732
Insert length:
5359 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse CIITA cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_001243760
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4639551
Datasheet
Catalog No. ABIN4639551
Type:
cDNA
Application:
Cloning
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_001243760
Species:
Mouse
Synonyms:
CIITA, LOC710761, ciita, LOC100443575, Ciita, LOC100736732
Insert length:
3465 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse CIITA cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_001243760
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4719901
Datasheet
Catalog No. ABIN4719901
Type:
cDNA
Application:
Cloning
Gene:
Class II, Major Histocompatibility Complex, Transactivator (CIITA)
NCBI Accession:
NM_001243760
Species:
Mouse
Synonyms:
CIITA, LOC710761, ciita, LOC100443575, Ciita, LOC100736732
Insert length:
5359 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Mouse
    • Human
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • Myc-DYKDDDDK Tag
    • GFP tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pCMV6-XL5
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • Enhanced CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to CIITA

  • class II, major histocompatibility complex, transactivator (CIITA)
  • class II major histocompatibility complex transactivator (CIITA)
  • MHC class II transactivator (LOC710761)
  • class II, major histocompatibility complex, transactivator (ciita)
  • MHC class II transactivator (LOC100443575)
  • class II transactivator (Ciita)
  • MHC class II transactivator (LOC100736732)
  • class II, major histocompatibility complex, transactivator (Ciita)
  • C2ta
  • C2TA
  • CIITA
  • CIITAIV
  • EG669998
  • Gm9475
  • MHC2TA
  • Mhc2ta
  • NLRA

Gene-IDs for different species

Protein level used designations for CIITA

  • class II, major histocompatibility complex, transactivator
  • class II transactivator-like
  • class II transactivator
  • MHC class II transactivator-like
  • MHC class II transactivator
  • MHC class II transactivator type III
  • NLR family, acid domain containing
  • nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing
  • MHC class II transactivator type IV
Other products related to CIITA such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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