Complement Factor B (Complement Factor B, CFB)
Short Description: This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008].
More information related to gene Complement Factor B.
More information related to gene Complement Factor B.
Products related to Complement Factor B Gene:
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62 results
OriGene sr300428
RNAi
CFB
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Complement Factor B
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3340222
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5313675
$226.33
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 19 Business Days
Synonyms and alternative names related to Complement Factor B
- complement factor B (CFB)
- complement factor B (cfb)
- complement factor B (bf)
- complement factor B S homeolog (cfb.S)
- complement factor B L homeolog (cfb.L)
- complement factor B (bf/c2)
- complement factor B (LOC100555981)
- complement factor B (Cfb)
- AHUS4
- AI195813
- AI255840
- B
- BF
- bf
- Bf
- Bf-1
- bf/c2
- Bf B
- bfb-A
- BFD
- Brre-Bf
- C2
- CFAB
- CFB
- Da1-24
- FB
- Fb
- FBI12
- GBG
- H2-Bf
- LOC397725
- PBF2
- Sp152
- zgc:114032
Gene-IDs for different species
Protein level used designations for Complement Factor B
- B-factor, properdin
- C3 proaccelerator
- C3 proactivator
- C3/C5 convertase
- glycine-rich beta glycoprotein
- glycine-rich beta-glycoprotein
- properdin factor B
- complement component factor B
- complement factor B
- complement component 2
- EC-VMFB
- complement factor Bf-1
- Factor B
- alternative-complement pathway C3/C5 convertase
- complement component 2 (within H-2S)
- histocompatibility 2, complement component factor B
- properdin
Proteomics products related to Complement Factor B Gene
Other products related to Complement Factor B such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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