Complement Factor I (Complement Factor I, CFI)
Short Description: This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene. [provided by RefSeq, Jul 2008].
More information related to gene Complement Factor I.
More information related to gene Complement Factor I.
Products related to Complement Factor I Gene:
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57 results
OriGene rg216645
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Complement Factor I (CFI)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5344237
$484.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rr200877
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Complement Factor I (CFI)
- NCBI Accession:
- NM_024157,NP_077071
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5344239
$611.82
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc216645
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Complement Factor I (CFI)
- NCBI Accession:
- NM_000204,NP_000195
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5344238
$537.57
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc216645l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Complement Factor I (CFI)
- NCBI Accession:
- NM_000204,NP_000195
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5344240
$834.57
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc216645l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Complement Factor I (CFI)
- NCBI Accession:
- NM_000204,NP_000195
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5344242
$834.57
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Complement Factor I (CFI)
- NCBI Accession:
- NM_000204
- Gene ID:
- 3426 (Human, CFI)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4931477
$489.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
OriGene sr302313
RNAi
CFI
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Complement Factor I
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3342095
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to Complement Factor I
- complement factor I S homeolog (cfi.S)
- complement factor I L homeolog (cfi.L)
- complement factor I (CFI)
- complement factor I (cfi)
- complement component factor i (Cfi)
- complement factor I (Cfi)
- ahus3
- AHUS3
- c3b-ina
- C3b-INA
- c3bc4bi
- c3bina
- C3BINA
- cfi
- Cfi
- CFI
- factor I
- FI
- gb:ai721528
- IF
- kaf
- KAF
- MGC53615
Gene-IDs for different species
Protein level used designations for Complement Factor I
- complement factor I
- I factor (complement)
- complement factor 1
- C3B/C4B inactivator
- C3b-inactivator
- Konglutinogen-activating factor
- complement component I
- complement control protein factor I
- complement factor I heavy chain
- light chain of factor I
- complement component 1
Proteomics products related to Complement Factor I Gene
Other products related to Complement Factor I such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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