CRYAB (Crystallin, alpha B, CRYAB)
Short Description: Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families\; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone\; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits\; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed\; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases\; a missense mutation cosegregated in a family with a desmin-related myopathy. [provided by RefSeq, Jul 2008].
More information related to gene CRYAB.
More information related to gene CRYAB.
Products related to CRYAB Gene:
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69 results
OriGene rc202718l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Crystallin, alpha B (CRYAB)
- NCBI Accession:
- NM_001885,NP_001876
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5398658
$594.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc202718l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Crystallin, alpha B (CRYAB)
- NCBI Accession:
- NM_001885,NP_001876
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5398660
$594.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rr213783l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Crystallin, alpha B (CRYAB)
- NCBI Accession:
- NM_012935,NP_037067
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5398661
$594.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
OriGene rr213783
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Crystallin, alpha B (CRYAB)
- NCBI Accession:
- NM_012935,NP_037067
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5398657
$286.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene rr213783l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Crystallin, alpha B (CRYAB)
- NCBI Accession:
- NM_012935,NP_037067
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5398659
$594.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
OriGene rc202718
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Crystallin, alpha B (CRYAB)
- NCBI Accession:
- NM_001885,NP_001876
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5398654
$297.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc236287
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Crystallin, alpha B (CRYAB)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5398656
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr404155
RNAi
CRYAB
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Crystallin, alpha B
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3278155
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr300995
RNAi
CRYAB
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Crystallin, alpha B
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3340783
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to CRYAB
- crystallin alpha B (CRYAB)
- crystallin, alpha B (Cryab)
- hypothetical protein (ZK1128.7)
- crystallin alpha B (Cryab)
- crystallin, alpha B, a (cryaba)
- crystallin, alpha B, b (cryabb)
- AACRYA
- CMD1II
- Crya-2
- CRYA2
- Crya2
- CRYAB
- cryab
- cryab2
- CTPP2
- CTRCT16
- HSPB5
- HspB5
- MFM2
- wu:fe37f08
- zgc:91937
Gene-IDs for different species
Protein level used designations for CRYAB
- alpha-crystallin B chain
- heat shock protein beta-5
- heat-shock 20 kD like-protein
- renal carcinoma antigen NY-REN-27
- rosenthal fiber component
- P23
- alpha B-crystallin
- alpha(B)-crystallin
- crystallin, alpha 2
- Crystallin, alpha polypeptide 2
- hypothetical protein
- crystallin, alpha B
- alpha B crystallin
- alpha-B-crystallin
- alphaB-crystallin
- crystallin, alpha polypeptide 2
- Alpha(B)-crystallin
- Alpha-crystallin B chain
- hspb5
- hspb5a
- alphaB2-crystallin
- crystallin alphaB-b
- crystallin, alpha B2
- fe37f08
- hspb5b
Proteomics products related to CRYAB Gene
Other products related to CRYAB such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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