CSK (C-Src tyrosine Kinase, CSK)
Short Description: Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T- cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK (By similarity).
More information related to gene CSK.
More information related to gene CSK.
Products related to CSK Gene:
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OriGene rg225740
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- C-Src tyrosine Kinase (CSK)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5430623
$722.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to CSK
- C-terminal Src kinase (CSK)
- c-src tyrosine kinase (Csk)
- C-terminal Src kinase (Csk)
- c-src tyrosine kinase (CSK)
- CSK, non-receptor tyrosine kinase (CSK)
- AW212630
Gene-IDs for different species
Protein level used designations for CSK
- C-Src kinase
- protein-tyrosine kinase CYL
- tyrosine-protein kinase CSK
- p50CSK
- protein-tyrosine kinase MPK-2
- C-SRC kinase
- protein-tyrosine kinase (CSK)
- protein kinase
- src kinase
Proteomics products related to CSK Gene
Other products related to CSK such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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