Cyclin E1 (Cyclin E1, CCNE1)
Short Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available. [provided by RefSeq, Jul 2008].
More information related to gene Cyclin E1.
More information related to gene Cyclin E1.
Products related to Cyclin E1 Gene:
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65 results
OriGene rr201927
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cyclin E1 (CCNE1)
- NCBI Accession:
- NM_001100821,NP_001094291
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5340934
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc204289l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cyclin E1 (CCNE1)
- NCBI Accession:
- NM_001238,NP_001229
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5340935
$749.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc213217
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Cyclin E1 (CCNE1)
- NCBI Accession:
- NM_057182,NP_476530
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5340933
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr300631
RNAi
CCNE1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Cyclin E1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3340424
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5320972
$215.19
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 19 Business Days
Synonyms and alternative names related to Cyclin E1
- cyclin E1 (CCNE1)
- cyclin E1 (ccne1)
- cyclin E1 (Ccne1)
- cyclin E1 L homeolog (ccne1.L)
- cyclin E1 S homeolog (ccne1.S)
- AW538188
- ccne
- CCNE
- Ccne
- CCNE1
- cyce
- CycE1
- cyce2
- cycE3
- CYCLE
- cyclinE
- fa18e07
- wu:fa18e07
Gene-IDs for different species
Protein level used designations for Cyclin E1
- cyclin E1
- G1/S-specific cyclin-E1
- G1/S-specific cyclin-E1-like
- g1/S-specific cyclin-E1-like
- cyclin Es
- cyclin Et
- cyclin E
- G1/S-specific cyclin-E2
- cyclin-E-1
- G1/S-specific cyclin-E3
- cyclin E3
Proteomics products related to Cyclin E1 Gene
Other products related to Cyclin E1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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