DC-SIGN/CD209 (CD209, CD209)
Short Description: This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 10332\; often referred to as L-SIGN). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.[provided by RefSeq, Feb 2009].
More information related to gene DC-SIGN/CD209.
More information related to gene DC-SIGN/CD209.
Products related to DC-SIGN/CD209 Gene:
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OriGene rc227875
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- CD209 Molecule (CD209)
- NCBI Accession:
- NM_001144894,NP_001138366
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5399202
$286.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 31 to 32 Business Days
OriGene rc226518
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- CD209 Molecule (CD209)
- NCBI Accession:
- NM_001144895,NP_001138367
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5399197
$286.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 41 to 42 Business Days
OriGene rc220486l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- CD209 Molecule (CD209)
- NCBI Accession:
- NM_021155,NP_066978
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5399208
$749.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc220486l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- CD209 Molecule (CD209)
- NCBI Accession:
- NM_021155,NP_066978
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5399203
$749.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr309363
RNAi
CD209
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- CD209
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3285399
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to DC-SIGN/CD209
- CD209 molecule (CD209)
- CD209 molecule (cd209)
- CD209a antigen (Cd209a)
- CD209 antigen-like protein D (LOC100529184)
- CD209c molecule (Cd209c)
- CD209 antigen (LOC100460708)
- CD209 antigen (LOC105484282)
- cd209
- CD209
- Cd209
- CDSIGN
- CIRE
- CLEC4L
- CLEC4M
- DC-SIGN
- DC-SIGN1
- Dcsign
- si:ch211-224h1.3
- SIGN-R1
- SIGNR5
Gene-IDs for different species
Protein level used designations for DC-SIGN/CD209
- C-type lectin domain family 4 member L
- C-type lectin domain family 4, member L
- CD209 antigen
- HIV gpl20-binding protein
- dendritic cell-specific ICAM-3-grabbing non-integrin 1
- dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin
- CD209-like protein
- DC-SIGN1
- dendritic cell-specific ICAM-3 grabbing non-integrin
- C-type lectin domain family 4, member M
- DC-SIGN protein
- putative mannose-binding C-type lectin
- CD209 antigen-like protein A
- dendritic cell-specific ICAM-3-grabbing non-integrin
- CD209
- CD209 antigen-like protein C
- CD209c antigen
- Dendritic cell-specific ICAM-3-grabbing non-integrin 1
- dendritic cell-specific ICAM-3 grabbing nonintegrin
Proteomics products related to DC-SIGN/CD209 Gene
Other products related to DC-SIGN/CD209 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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