DCLK1 (Doublecortin-Like Kinase 1, DCLK1)
Short Description: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.[provided by RefSeq, Sep 2010].
More information related to gene DCLK1.
More information related to gene DCLK1.
Products related to DCLK1 Gene:
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OriGene kn217050
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Doublecortin-Like Kinase 1 (DCLK1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3252743
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 10 to 12 Business Days
Synonyms and alternative names related to DCLK1
- doublecortin like kinase 1 (DCLK1)
- doublecortin-like kinase 1a (dclk1a)
- serine/threonine-protein kinase DCLK1 (LOC587664)
- doublecortin-like kinase 2 (dclk2)
- serine/threonine-protein kinase DCLK1 (LOC100539645)
- doublecortin-like kinase 1 (Dclk1)
- doublecortin-like kinase 1 (DCLK1)
- doublecortin like kinase 1 (Dclk1)
- 1700113D08Rik
- 2810480F11Rik
- AI836758
- Ania4
- CL1
- Click-I
- CLICK1
- Cpg16
- DCAMKL1
- dcamkl1
- Dcamkl1
- DCDC3A
- Dcl
- DCLK
- Dclk
- DCLK1
- dclk1
- MGC145348
- mKIAA0369
- wu:fc51f11
- zgc:153709
Gene-IDs for different species
Protein level used designations for DCLK1
- doublecortin-like kinase 1
- doublecortin and CaM kinase-like 1
- doublecortin and calcium/calmodulin-dependent protein kinase-like 1
- serine/threonine-protein kinase DCLK1
- doublecortin-like kinase 2
- serine/threonine-protein kinase DCLK1-like
- doublecortin domain-containing protein 3A
- doublecortin-like and CAM kinase-like 1
- CLICK-I beta
- double cortin and calcium/calmodulin-dependent protein kinase-like 1
Proteomics products related to DCLK1 Gene
Other products related to DCLK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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