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DCLK1 (Doublecortin-Like Kinase 1, DCLK1)

Short Description: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.[provided by RefSeq, Sep 2010].
More information related to gene DCLK1.

Products related to DCLK1 Gene:

91 results :

Human DCLK1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_004734
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5739781
Datasheet
Catalog No. ABIN5739781
Type:
ORF
Application:
Cloning
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_004734
Species:
Human
Synonyms:
DCLK1, dclk1a, LOC587664, dclk2, LOC100539645, Dclk1
Insert length:
2190 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human DCLK1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_004734
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4487684
Datasheet
Catalog No. ABIN4487684
Type:
cDNA
Application:
Protein Expression
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_004734
Species:
Human
Synonyms:
DCLK1, dclk1a, LOC587664, dclk2, LOC100539645, Dclk1
Insert length:
2190 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat DCLK1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_053343
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5232812
Datasheet
Catalog No. ABIN5232812
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_053343
Species:
Rat
Synonyms:
DCLK1, dclk1a, LOC587664, dclk2, LOC100539645, Dclk1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dclk1
Format:
Viral Particles
Storage:
-80 °C
Mouse DCLK1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_019978
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5232810
Datasheet
Catalog No. ABIN5232810
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_019978
Species:
Mouse
Synonyms:
DCLK1, dclk1a, LOC587664, dclk2, LOC100539645, Dclk1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dclk1
Format:
Viral Particles
Storage:
-80 °C
Human DCLK1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_004734
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5232808
Datasheet
Catalog No. ABIN5232808
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_004734
Species:
Human
Synonyms:
DCLK1, dclk1a, LOC587664, dclk2, LOC100539645, Dclk1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of DCLK1
Format:
Viral Particles
Storage:
-80 °C
Rat DCLK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_053343
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5117454
Datasheet
Catalog No. ABIN5117454
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_053343
Species:
Rat
Synonyms:
DCLK1, dclk1a, LOC587664, dclk2, LOC100539645, Dclk1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dclk1
Format:
Viral Particles
Storage:
-80 °C
Mouse DCLK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_019978
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5117452
Datasheet
Catalog No. ABIN5117452
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_019978
Species:
Mouse
Synonyms:
DCLK1, dclk1a, LOC587664, dclk2, LOC100539645, Dclk1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dclk1
Format:
Viral Particles
Storage:
-80 °C
Human DCLK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_004734
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5117450
Datasheet
Catalog No. ABIN5117450
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_004734
Species:
Human
Synonyms:
DCLK1, dclk1a, LOC587664, dclk2, LOC100539645, Dclk1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of DCLK1
Format:
Viral Particles
Storage:
-80 °C
Human DCLK1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_004734
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4829947
Datasheet
Catalog No. ABIN4829947
Type:
cDNA
Application:
Cloning
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_004734
Species:
Human
Synonyms:
DCLK1, dclk1a, LOC587664, dclk2, LOC100539645, Dclk1
Insert length:
2190 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human DCLK1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_004734
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4700818
Datasheet
Catalog No. ABIN4700818
Type:
cDNA
Application:
Cloning
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_004734
Species:
Human
Synonyms:
DCLK1, dclk1a, LOC587664, dclk2, LOC100539645, Dclk1
Insert length:
2190 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRFP-C-RS
    • pRS
    • pCas-Guide
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to DCLK1

  • doublecortin like kinase 1 (DCLK1)
  • doublecortin-like kinase 1a (dclk1a)
  • serine/threonine-protein kinase DCLK1 (LOC587664)
  • doublecortin-like kinase 2 (dclk2)
  • serine/threonine-protein kinase DCLK1 (LOC100539645)
  • doublecortin-like kinase 1 (Dclk1)
  • doublecortin-like kinase 1 (DCLK1)
  • doublecortin like kinase 1 (Dclk1)
  • 1700113D08Rik
  • 2810480F11Rik
  • AI836758
  • Ania4
  • CL1
  • Click-I
  • CLICK1
  • Cpg16
  • DCAMKL1
  • dcamkl1
  • Dcamkl1
  • DCDC3A
  • Dcl
  • DCLK
  • Dclk
  • DCLK1
  • dclk1
  • MGC145348
  • mKIAA0369
  • wu:fc51f11
  • zgc:153709

Gene-IDs for different species

Protein level used designations for DCLK1

  • doublecortin-like kinase 1
  • doublecortin and CaM kinase-like 1
  • doublecortin and calcium/calmodulin-dependent protein kinase-like 1
  • serine/threonine-protein kinase DCLK1
  • doublecortin-like kinase 2
  • serine/threonine-protein kinase DCLK1-like
  • doublecortin domain-containing protein 3A
  • doublecortin-like and CAM kinase-like 1
  • CLICK-I beta
  • double cortin and calcium/calmodulin-dependent protein kinase-like 1
Other products related to DCLK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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