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DCLK1 (Doublecortin-Like Kinase 1, DCLK1)

Short Description: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.[provided by RefSeq, Sep 2010].
More information related to gene DCLK1.

Products related to DCLK1 Gene:

91 results

OriGene tg515725 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3697716
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tf515725 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3678017
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tg320606 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3744395
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tg711780 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3505985
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tf711780 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3492054
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene mc221217 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_001195538,NP_001182467
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3322901
$738.54
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 31 Business Days
OriGene mc221361 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_019978,NP_064362
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3322902
$754.38
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 31 Business Days
OriGene tf320606 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3724057
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 8 Business Days
OriGene tr320606 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3661492
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tr515725 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3548724
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRFP-C-RS
    • pRS
    • pCas-Guide
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to DCLK1

  • doublecortin like kinase 1 (DCLK1)
  • doublecortin-like kinase 1a (dclk1a)
  • serine/threonine-protein kinase DCLK1 (LOC587664)
  • doublecortin-like kinase 2 (dclk2)
  • serine/threonine-protein kinase DCLK1 (LOC100539645)
  • doublecortin-like kinase 1 (Dclk1)
  • doublecortin-like kinase 1 (DCLK1)
  • doublecortin like kinase 1 (Dclk1)
  • 1700113D08Rik
  • 2810480F11Rik
  • AI836758
  • Ania4
  • CL1
  • Click-I
  • CLICK1
  • Cpg16
  • DCAMKL1
  • dcamkl1
  • Dcamkl1
  • DCDC3A
  • Dcl
  • DCLK
  • Dclk
  • DCLK1
  • dclk1
  • MGC145348
  • mKIAA0369
  • wu:fc51f11
  • zgc:153709

Gene-IDs for different species

Protein level used designations for DCLK1

  • doublecortin-like kinase 1
  • doublecortin and CaM kinase-like 1
  • doublecortin and calcium/calmodulin-dependent protein kinase-like 1
  • serine/threonine-protein kinase DCLK1
  • doublecortin-like kinase 2
  • serine/threonine-protein kinase DCLK1-like
  • doublecortin domain-containing protein 3A
  • doublecortin-like and CAM kinase-like 1
  • CLICK-I beta
  • double cortin and calcium/calmodulin-dependent protein kinase-like 1
Other products related to DCLK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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