Short Description: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]. More information related to gene Deoxyguanosine Kinase.
Synonyms and alternative names related to Deoxyguanosine Kinase
deoxyguanosine kinase (DGUOK)
deoxyguanosine kinase (dguok)
deoxyguanosine kinase L homeolog (dguok.L)
deoxyguanosine kinase (dgk)
deoxyguanosine kinase (Ccan_04750)
deoxyguanosine kinase (Dguok)
DDBDRAFT_0218264
DDBDRAFT_0233982
DDB_0218264
DDB_0233982
dgk
dGK
dGK1
dGK2
dGK3
DGUOK
MTDPS3
zgc:86625
Gene-IDs for different species
Protein level used designations for Deoxyguanosine Kinase
deoxyguanosine kinase
deoxyguanosine kinase, mitochondrial
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