DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide, DFFA)
Short Description: Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene DFFA.
More information related to gene DFFA.
Products related to DFFA Gene:
Recommended next Filters:
62 results
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA)
- NCBI Accession:
- NM_004401
- Gene ID:
- 1676 (Human, DFFA)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4940084
$199.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene sr301189
RNAi
DFFA
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- DNA Fragmentation Factor, 45kDa, alpha Polypeptide
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3340977
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to DFFA
- DNA fragmentation factor subunit alpha (DFFA)
- DNA fragmentation factor, alpha subunit (Dffa)
- DNA fragmentation factor, 45kDa, alpha polypeptide (dffa)
- DNA fragmentation factor subunit alpha (Dffa)
- DNA fragmentation factor, alpha polypeptide (dffa)
- A330085O09Rik
- DFF-45
- DFF1
- DFF35
- Dff45
- DFFA
- ICAD
- ICAD-L
- ICAD-S
- zgc:92229
Gene-IDs for different species
Protein level used designations for DFFA
- DFF45
- DNA fragmentation factor 45 kDa subunit
- DNA fragmentation factor subunit alpha
- inhibitor of CAD
- DFF-45
- DNA fragmentation factor, 45kDa, alpha polypeptide
Proteomics products related to DFFA Gene
Other products related to DFFA such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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