DIO2 (Deiodinase, Iodothyronine, Type II, DIO2)
Short Description: The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
More information related to gene DIO2.
More information related to gene DIO2.
Products related to DIO2 Gene:
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68 results
OriGene kn504583
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3253250
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn410376
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3253249
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr407615
RNAi
DIO2
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Deiodinase, Iodothyronine, Type II
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3281569
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr500918
RNAi
DIO2
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Deiodinase, Iodothyronine, Type II
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3351323
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene mc208391
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- NCBI Accession:
- NP_034180
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3290343
$468.27
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene rn201204
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- NCBI Accession:
- NM_031720,NP_113908
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3290344
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc301132
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- NCBI Accession:
- NM_001007023,NP_001007024
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3322510
$718.74
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc124708
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- NCBI Accession:
- NM_013989,NP_054644
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3383656
$718.74
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene sc119691
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL4
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- NCBI Accession:
- NM_000793,NP_000784
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL4
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3377743
$718.74
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- NCBI Accession:
- NM_000793
- Gene ID:
- 1734 (Human, DIO2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4919945
$199.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
Synonyms and alternative names related to DIO2
- iodothyronine deiodinase 2 (DIO2)
- deiodinase, iodothyronine, type II (Dio2)
- iodothyronine deiodinase 2 (dio2)
- deiodinase, iodothyronine, type II (dio2)
- deiodinase, iodothyronine, type 2 L homeolog (dio2.L)
- deiodinase, iodothyronine, type 2 (dio2)
- iodothyronine deiodinase 2 (Dio2)
- type II iodothyronine deiodinase (LOC100861220)
- 5DII
- 5dii
- AI324267
- cb684
- D2
- Deio2
- DIO2
- dio2-A
- DIOII
- SelY
- sely
- TXDI2
- txdi2
Gene-IDs for different species
Protein level used designations for DIO2
- thyroxine deiodinase, type II
- type 2 DI
- type 2 iodothyronine deiodinase
- type II iodothyronine deiodinase
- type-II 5'-deiodinase
- type-II 5'deiodinase
- iodothyronine type II deiodinase
- type-II 5' deiodinase
- deiodinase, iodothyronine, type 2
- D2
- 5DII
- DIOII
- deiodinase, iodothyronine, type II
- deiodinase 2
- type 2 deiodinase
Proteomics products related to DIO2 Gene
Other products related to DIO2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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