DIO2 (Deiodinase, Iodothyronine, Type II, DIO2)
Short Description: The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
More information related to gene DIO2.
More information related to gene DIO2.
Products related to DIO2 Gene:
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68 results
OriGene rc213149l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- NCBI Accession:
- NM_001007023,NP_001007024
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5345086
$742.50
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rg231826
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5345074
$361.35
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc214679
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- NCBI Accession:
- NM_013989,NP_054644
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5345077
$445.50
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc214679l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- NCBI Accession:
- NM_013989,NP_054644
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5345087
$742.50
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- NCBI Accession:
- NM_001242502
- Gene ID:
- 1734 (Human, DIO2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4930548
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- NCBI Accession:
- NM_001242503
- Gene ID:
- 1734 (Human, DIO2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4930549
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Deiodinase, Iodothyronine, Type II (DIO2)
- NCBI Accession:
- NM_001007023
- Gene ID:
- 1734 (Human, DIO2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4940046
$199.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene sr301206
RNAi
DIO2
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Deiodinase, Iodothyronine, Type II
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3340994
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to DIO2
- iodothyronine deiodinase 2 (DIO2)
- deiodinase, iodothyronine, type II (Dio2)
- iodothyronine deiodinase 2 (dio2)
- deiodinase, iodothyronine, type II (dio2)
- deiodinase, iodothyronine, type 2 L homeolog (dio2.L)
- deiodinase, iodothyronine, type 2 (dio2)
- iodothyronine deiodinase 2 (Dio2)
- type II iodothyronine deiodinase (LOC100861220)
- 5DII
- 5dii
- AI324267
- cb684
- D2
- Deio2
- DIO2
- dio2-A
- DIOII
- SelY
- sely
- TXDI2
- txdi2
Gene-IDs for different species
Protein level used designations for DIO2
- thyroxine deiodinase, type II
- type 2 DI
- type 2 iodothyronine deiodinase
- type II iodothyronine deiodinase
- type-II 5'-deiodinase
- type-II 5'deiodinase
- iodothyronine type II deiodinase
- type-II 5' deiodinase
- deiodinase, iodothyronine, type 2
- D2
- 5DII
- DIOII
- deiodinase, iodothyronine, type II
- deiodinase 2
- type 2 deiodinase
Proteomics products related to DIO2 Gene
Other products related to DIO2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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