DOCK3 (Dedicator of Cytokinesis 3, DOCK3)
Short Description: This gene is specifically expressed in the central nervous system (CNS). It encodes a member of the DOCK (dedicator of cytokinesis) family of guanine nucleotide exchange factors (GEFs). This protein, dedicator of cytokinesis 3 (DOCK3), is also known as modifier of cell adhesion (MOCA) and presenilin-binding protein (PBP). The DOCK3 and DOCK1, -2 and -4 share several conserved amino acids in their DHR-2 (DOCK homology region 2) domains that are required for GEF activity, and bind directly to WAVE proteins [Wiskott-Aldrich syndrome protein (WASP) family Verprolin-homologous proteins] via their DHR-1 domains. The DOCK3 induces axonal outgrowth in CNS by stimulating membrane recruitment of the WAVE complex and activating the small G protein Rac1. This gene is associated with an attention deficit hyperactivity disorder-like phenotype by a complex chromosomal rearrangement. [provided by RefSeq, Aug 2010].
More information related to gene DOCK3.
More information related to gene DOCK3.
Products related to DOCK3 Gene:
Recommended next Filters:
41 results
OriGene sr301251
RNAi
DOCK3
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Dedicator of Cytokinesis 3
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3341038
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to DOCK3
- dedicator of cytokinesis 3 (DOCK3)
- similar to dedicator of cytokinesis 3 (LOC561387)
- dedicator of cytokinesis 3 (dock3)
- dedicator of cytokinesis protein 3 (LOC100474164)
- dedicator of cyto-kinesis 3 (Dock3)
- mKIAA0299
- MOCA
- PBP
Gene-IDs for different species
Protein level used designations for DOCK3
- dedicator of cytokinesis 3
- similar to dedicator of cytokinesis 3
- dedicator of cytokinesis protein 3-like
- dedicator of cytokinesis protein 3
- modifier of cell adhesion
- presenilin-binding protein
Proteomics products related to DOCK3 Gene
Other products related to DOCK3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:
