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DUSP4 (Dual Specificity Phosphatase 4, DUSP4)

Short Description: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported. [provided by RefSeq, Jul 2008].
More information related to gene DUSP4.

Products related to DUSP4 Gene:

66 results

gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual Specificity Phosphatase 4 (DUSP4)
NCBI Accession:
NM_001394
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5202597
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual Specificity Phosphatase 4 (DUSP4)
NCBI Accession:
NM_022199
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5202603
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
ORF Clon Gateway Cloning Vector pDONR223 Spectinomycin unconjugated
Type:
ORF
Application:
Cloning
Gene:
Dual Specificity Phosphatase 4 (DUSP4)
Gene ID:
1846 (Human, DUSP4)
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin
Catalog No. ABIN5316930
$223.79
Plus shipping costs $50.00
2 μg
Shipping to: United States
Delivery in 15 to 19 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Dual Specificity Phosphatase 4 (DUSP4)
NCBI Accession:
NM_057158
Gene ID:
1846 (Human, DUSP4)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4930350
$199.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
OriGene sc125374 cDNA PExp Mammalian Expression Vector pCMV6-XL4 Ampicillin Enhanced CMV Promoter unconjugated Transient
Pubmed 1
Type:
cDNA
Application:
Protein Expression
Gene:
Dual Specificity Phosphatase 4 (DUSP4)
NCBI Accession:
NM_057158,NP_476499
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL4
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3381125
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene rc215252 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Dual Specificity Phosphatase 4 (DUSP4)
NCBI Accession:
NM_057158,NP_476499
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5345633
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
OriGene mc214414 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Dual Specificity Phosphatase 4 (DUSP4)
NCBI Accession:
NP_795907
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3290963
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene rg215252 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Dual Specificity Phosphatase 4 (DUSP4)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5345631
$484.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
OriGene rn209242 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Dual Specificity Phosphatase 4 (DUSP4)
NCBI Accession:
NM_022199,NP_071535
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3290964
$497.97
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene rr209242 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Dual Specificity Phosphatase 4 (DUSP4)
NCBI Accession:
NM_022199,NP_071535
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5345634
$497.97
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-U6-sgRNA-PGK-Neo
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pCMV6-XL4
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to DUSP4

  • dual specificity phosphatase 4 (dusp4)
  • dual specificity phosphatase 4 (DUSP4)
  • dual specificity phosphatase 4 S homeolog (dusp4.S)
  • dual specificity phosphatase 4 (Dusp4)
  • 2700078F24Rik
  • AI844617
  • BB104621
  • DUSP4
  • E130306H24Rik
  • hvh2
  • HVH2
  • MGC131045
  • mkp-2
  • MKP-2
  • Mkp-2
  • mkp2
  • MKP2
  • Mkp2
  • typ
  • TYP
  • zgc:55423

Gene-IDs for different species

Protein level used designations for DUSP4

  • dual specificity protein phosphatase 4
  • dual specificity phosphatase 4
  • MAP kinase phosphatase 2
  • VH1 homologous phosphatase 2
  • dual specificity protein phosphatase hVH2
  • mitogen-activated protein kinase phosphatase 2
  • serine/threonine specific protein phosphatase
Other products related to DUSP4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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