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Dystrophin (Dystrophin, DMD)

Short Description: The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level. The dystrophin gene is highly complex, containing at least eight independent, tissue-specific promoters and two polyA-addition sites. Furthermore, dystrophin RNA is differentially spliced, producing a range of different transcripts, encoding a large set of protein isoforms. Dystrophin (as encoded by the Dp427 transcripts) is a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers. Dystrophin is part of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton (F-actin) and the extra-cellular matrix. [provided by RefSeq, Jul 2008].
More information related to gene Dystrophin.

Products related to Dystrophin Gene:

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109 results

Human DMD ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc220475 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Dystrophin (DMD)
NCBI Accession:
NM_004017,NP_004008
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5384052
$556.38
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human DMD ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc222424 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Dystrophin (DMD)
NCBI Accession:
NM_004015,NP_004006
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5384055
$568.26
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human DMD ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Dystrophin (DMD)
NCBI Accession:
NM_004018
Gene ID:
1756 (Human, DMD)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4930514
$519.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
Details
Details
Human DMD ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Dystrophin (DMD)
NCBI Accession:
NM_004017
Gene ID:
1756 (Human, DMD)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4930515
$509.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
Details
Details
Human DMD ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Dystrophin (DMD)
NCBI Accession:
NM_004016
Gene ID:
1756 (Human, DMD)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4930516
$99.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
Details
Details
Human DMD ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Dystrophin (DMD)
NCBI Accession:
NM_004014
Gene ID:
1756 (Human, DMD)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4944092
$939.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
Details
Details
Human DMD ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Dystrophin (DMD)
NCBI Accession:
NM_004023
Gene ID:
1756 (Human, DMD)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4946001
$1,139.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 2 to 5 Business Days
Details
Details
Human DMD ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Dystrophin (DMD)
NCBI Accession:
NM_004021
Gene ID:
1756 (Human, DMD)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4946003
$1,249.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 2 to 5 Business Days
Details
Details
Human DMD ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Dystrophin (DMD)
NCBI Accession:
NM_004020
Gene ID:
1756 (Human, DMD)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4946004
$1,129.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 2 to 5 Business Days
Details
Details
Human DMD ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Dystrophin (DMD)
NCBI Accession:
NM_004022
Gene ID:
1756 (Human, DMD)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4946002
$1,249.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 2 to 5 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • His tag
    • His-GST
    • His-MBP
    • HA tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pPB-His-GST
    • pPB-His-MBP
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pRFP-C-RS
    • pCMV6-XL4
    • pCMV6-XL6
    • pCas-Guide
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to Dystrophin

  • dystrophin (DMD)
  • dystrophin (LOC708073)
  • dystrophin, gene 1 L homeolog (dmd.1.L)
  • dystrophin (LOC465557)
  • dystrophin, gene 1 (dmd.1)
  • dystrophin (dmd)
  • dystrophin, muscular dystrophy (Dmd)
  • dystrophin (Dmd)
  • Dystrophin (Dys)
  • BMD
  • cb664
  • CG7240
  • CG7243
  • CG7344
  • CG17750
  • CG31175
  • CG34157
  • CMD3B
  • det
  • DKFZp459C1629
  • DKFZp468A1620
  • DLP
  • DLP1
  • DLP2
  • DLP3
  • DLP186
  • DMD
  • Dmd
  • dmd
  • DmDLP
  • dmDLP
  • dmDp186
  • DmDYS
  • dmDys
  • Dmel\\CG34157
  • DNADMD1
  • Dp71
  • Dp117
  • Dp186
  • Dp205
  • Dp427
  • DXS142
  • DXS164
  • DXS206
  • DXS230
  • DXS239
  • DXS268
  • DXS269
  • DXS270
  • DXS272
  • DXSmh7
  • DXSmh9
  • dys
  • GI3046716
  • IDLP
  • im:6911785
  • mdx
  • MGC79631
  • MGC83347
  • pke
  • RATDMD
  • zfDYS
  • zgc:110165

Gene-IDs for different species

Protein level used designations for Dystrophin

  • dystrophin (muscular dystrophy, Duchenne and Becker types)
  • dystrophin
  • Duchenne muscular dystrophy
  • dystrophin isoform Dp116
  • sap
  • sapje
  • dystrophin Dp71 isoform
  • X-linked muscular dystrophy
  • RNDNADMD1
  • apodystrophin-3
  • apodystrophin-I
  • dystrophin transcript variant Dp71e
  • dystrophin, muscular dystrophy
  • CG34157-PA
  • CG34157-PB
  • CG34157-PC
  • CG34157-PD
  • CG34157-PE
  • CG34157-PF
  • CG34157-PG
  • CG34157-PH
  • CG34157-PI
  • CG34157-PJ
  • CG34157-PK
  • CG34157-PL
  • Dys-PA
  • Dys-PB
  • Dys-PC
  • Dys-PD
  • Dys-PE
  • Dys-PF
  • Dys-PG
  • Dys-PH
  • Dys-PI
  • Dys-PJ
  • Dys-PK
  • Dys-PL
  • Dystrophin-like protein 1
  • Dystrophin-like protein 186
  • Dystrophin-like protein 2
  • Dystrophin-like protein 3
  • detached
  • dystrophin Dp186
Other products related to Dystrophin such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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