Dystrophin (Dystrophin, DMD)
Short Description: The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level. The dystrophin gene is highly complex, containing at least eight independent, tissue-specific promoters and two polyA-addition sites. Furthermore, dystrophin RNA is differentially spliced, producing a range of different transcripts, encoding a large set of protein isoforms. Dystrophin (as encoded by the Dp427 transcripts) is a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers. Dystrophin is part of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton (F-actin) and the extra-cellular matrix. [provided by RefSeq, Jul 2008].
More information related to gene Dystrophin.
More information related to gene Dystrophin.
Products related to Dystrophin Gene:
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109 results
OriGene sr500221
RNAi
DMD
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Dystrophin
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3350734
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr423659
RNAi
DMD
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Dystrophin
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3350497
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl700634
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Dystrophin (DMD)
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3508796
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene rn200461
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Dystrophin (DMD)
- NCBI Accession:
- NM_001005246,NP_001005246
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3290455
$514.80
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn200463
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Dystrophin (DMD)
- NCBI Accession:
- NM_012698,NP_036830
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3290457
$612.81
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn200462
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Dystrophin (DMD)
- NCBI Accession:
- NM_001005244,NP_001005244
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3290456
$631.62
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc313019
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Dystrophin (DMD)
- NCBI Accession:
- NM_004019,NP_004010
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3322511
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc314209
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Dystrophin (DMD)
- NCBI Accession:
- NM_004015,NP_004006
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3322513
$626.67
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc314163
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Dystrophin (DMD)
- NCBI Accession:
- NM_004017,NP_004008
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3322512
$612.81
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc314282
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Dystrophin (DMD)
- NCBI Accession:
- NM_004016,NP_004007
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3322514
$644.49
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to Dystrophin
- dystrophin (DMD)
- dystrophin (LOC708073)
- dystrophin, gene 1 L homeolog (dmd.1.L)
- dystrophin (LOC465557)
- dystrophin, gene 1 (dmd.1)
- dystrophin (dmd)
- dystrophin, muscular dystrophy (Dmd)
- dystrophin (Dmd)
- Dystrophin (Dys)
- BMD
- cb664
- CG7240
- CG7243
- CG7344
- CG17750
- CG31175
- CG34157
- CMD3B
- det
- DKFZp459C1629
- DKFZp468A1620
- DLP
- DLP1
- DLP2
- DLP3
- DLP186
- DMD
- Dmd
- dmd
- DmDLP
- dmDLP
- dmDp186
- DmDYS
- dmDys
- Dmel\\CG34157
- DNADMD1
- Dp71
- Dp117
- Dp186
- Dp205
- Dp427
- DXS142
- DXS164
- DXS206
- DXS230
- DXS239
- DXS268
- DXS269
- DXS270
- DXS272
- DXSmh7
- DXSmh9
- dys
- GI3046716
- IDLP
- im:6911785
- mdx
- MGC79631
- MGC83347
- pke
- RATDMD
- zfDYS
- zgc:110165
Gene-IDs for different species
Protein level used designations for Dystrophin
- dystrophin (muscular dystrophy, Duchenne and Becker types)
- dystrophin
- Duchenne muscular dystrophy
- dystrophin isoform Dp116
- sap
- sapje
- dystrophin Dp71 isoform
- X-linked muscular dystrophy
- RNDNADMD1
- apodystrophin-3
- apodystrophin-I
- dystrophin transcript variant Dp71e
- dystrophin, muscular dystrophy
- CG34157-PA
- CG34157-PB
- CG34157-PC
- CG34157-PD
- CG34157-PE
- CG34157-PF
- CG34157-PG
- CG34157-PH
- CG34157-PI
- CG34157-PJ
- CG34157-PK
- CG34157-PL
- Dys-PA
- Dys-PB
- Dys-PC
- Dys-PD
- Dys-PE
- Dys-PF
- Dys-PG
- Dys-PH
- Dys-PI
- Dys-PJ
- Dys-PK
- Dys-PL
- Dystrophin-like protein 1
- Dystrophin-like protein 186
- Dystrophin-like protein 2
- Dystrophin-like protein 3
- detached
- dystrophin Dp186
Proteomics products related to Dystrophin Gene
Other products related to Dystrophin such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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