ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2, ErbB2/Her2)
Short Description: This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008].
More information related to gene ErbB2/Her2.
More information related to gene ErbB2/Her2.
Products related to ErbB2/Her2 Gene:
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OriGene rc212583l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ErbB2/Her2)
- NCBI Accession:
- NM_004448,NP_004439
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5430607
$1,378.08
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc222909l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ErbB2/Her2)
- NCBI Accession:
- NM_001005862,NP_001005862
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5430608
$1,880.01
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
OriGene rc222909l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ErbB2/Her2)
- NCBI Accession:
- NM_001005862,NP_001005862
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5430610
$1,880.01
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc222909
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ErbB2/Her2)
- NCBI Accession:
- NM_001005862,NP_001005862
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5430605
$583.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc212583l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ErbB2/Her2)
- NCBI Accession:
- NM_004448,NP_004439
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5430609
$1,378.08
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
Synonyms and alternative names related to ErbB2/Her2
- erb-b2 receptor tyrosine kinase 2 (ERBB2)
- erb-b2 receptor tyrosine kinase 2 (Erbb2)
- erb-b2 receptor tyrosine kinase 2 (erbb2)
- c-erbB2
- c-neu
- CD340
- erb2
- Erbb-2
- HER-2
- HER-2/neu
- HER2
- mKIAA3023
- MLN 19
- NEU
- Neu
- NGL
- TKR1
- wu:fv70f10
- zgc:63601
Gene-IDs for different species
Protein level used designations for ErbB2/Her2
- c-erb B2/neu protein
- herstatin
- metastatic lymph node gene 19 protein
- neuro/glioblastoma derived oncogene homolog
- neuroblastoma/glioblastoma derived oncogene homolog
- p185erbB2
- proto-oncogene Neu
- proto-oncogene c-ErbB-2
- receptor tyrosine-protein kinase erbB-2
- tyrosine kinase-type cell surface receptor HER2
- v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
- Neu oncogene
- avian erythroblastosis oncogene B 2
- c-erbB-2
- proto-oncogene NEU
- erbB-2
- Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog)
- C-erbB-2
- NEU proto-oncogene
- epidermal growth factor receptor-related protein
- p185neu
- v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
- epidermal growth factor receptor type 2
Proteomics products related to ErbB2/Her2 Gene
Other products related to ErbB2/Her2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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