Erythrocyte Ankyrin (Ankyrin 1, Erythrocytic, ANK1)
Short Description: Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats\; a central region with a highly conserved spectrin binding domain\; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting from usage of an alternate promoter have also been identified. [provided by RefSeq, Dec 2008].
More information related to gene Erythrocyte Ankyrin.
More information related to gene Erythrocyte Ankyrin.
Products related to Erythrocyte Ankyrin Gene:
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92 results
OriGene rg220763
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ankyrin 1, Erythrocytic (ANK1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5338351
$1,961.19
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
OriGene sr300200
RNAi
ANK1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Ankyrin 1, Erythrocytic
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3339995
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to Erythrocyte Ankyrin
- ankyrin 1 (ANK1)
- ankyrin 1, erythrocytic a (ank1a)
- ankyrin 1 (ank1)
- ankyrin 1 L homeolog (ank1.L)
- ankyrin 1, erythrocytic (ANK1)
- ankyrin 1 (Ank1)
- ankyrin 1, erythroid (Ank1)
- ank
- ANK
- Ank-1
- ANK1
- CHANK1
- nb
- pale
- sph1
- SPH1
- sph2
- SPH2
- wu:fa09h06
- zgc:101835
Gene-IDs for different species
Protein level used designations for Erythrocyte Ankyrin
- ankyrin 1, erythrocytic
- erythroid ankyrin
- ankyrin-1-like
- ANK-1
- ankyrin-1
- ankyrin-R
- erythrocyte ankyrin
- ankyrin 1, erythroid
- normoblastic anemia
Proteomics products related to Erythrocyte Ankyrin Gene
Other products related to Erythrocyte Ankyrin such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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