EXOSC10 (Exosome Component 10, EXOSC10)
Short Description: Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC10 has 3'-5' exonuclease activity (By similarity). EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of SKIV2L2, C1D and MPP6 wth the RNA exosome involved in the maturation of 5.8S rRNA (By similarity).
More information related to gene EXOSC10.
More information related to gene EXOSC10.
Products related to EXOSC10 Gene:
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45 results
OriGene rc213555
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Exosome Component 10 (EXOSC10)
- NCBI Accession:
- NM_002685,NP_002676
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5422648
$857.34
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
OriGene rc210055l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Exosome Component 10 (EXOSC10)
- NCBI Accession:
- NM_001001998,NP_001001998
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5422649
$1,098.90
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rg210055
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Exosome Component 10 (EXOSC10)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5422645
$781.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc210055l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Exosome Component 10 (EXOSC10)
- NCBI Accession:
- NM_001001998,NP_001001998
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5422651
$1,098.90
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr303600
RNAi
EXOSC10
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Exosome Component 10
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3343377
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to EXOSC10
- exosome component 10 (exosc10)
- exosome component 10 (EXOSC10)
- exosome component 10 (EHI_021400)
- exosome component 10 (BBOV_IV002650)
- exosome component 10 (CpipJ_CPIJ003896)
- exosome component 10 (CMU_031760)
- 3'-5' exonuclease (exosc10)
- exosome component 10 (Tsp_05247)
- exosome component 10 L homeolog (exosc10.L)
- exosome component 10 (Exosc10)
- 21.m02990
- 201.t00018
- DDBDRAFT_0203581
- DDBDRAFT_0233752
- DDB_0203581
- DDB_0233752
- EXOSC10
- p2
- p3
- p4
- pm-scl
- PM-Scl
- pm/scl-100
- PM/Scl-100
- pmscl
- PMSCL
- Pmscl2
- pmscl2
- PMSCL2
- rrp6
- RRP6
- rrp6p
- Rrp6p
- zgc:55695
Gene-IDs for different species
Protein level used designations for EXOSC10
- exosome component 10
- Exosome component 10
- P100 polymyositis-scleroderma overlap syndrome-associated autoantigen
- autoantigen PM-SCL
- autoantigen PM/Scl 2
- polymyositis/scleroderma autoantigen 100 kDa
- polymyositis/scleroderma autoantigen 2 (100kD)
- polymyositis/scleroderma autoantigen 2, 100kDa
- autoantigen PM/Scl 2 homolog
- polymyositis/scleroderma autoantigen 2 homolog
Proteomics products related to EXOSC10 Gene
Other products related to EXOSC10 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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