FAS (TNF Receptor Superfamily, Member 6, FAS)
Short Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011].
More information related to gene FAS.
More information related to gene FAS.
Products related to FAS Gene:
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74 results
OriGene rg211622
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- TNF Receptor Superfamily, Member 6 (FAS)
- NCBI Accession:
- NM_152872,NP_690611
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5401742
$673.20
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rg211839
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- TNF Receptor Superfamily, Member 6 (FAS)
- NCBI Accession:
- NM_152876,NP_690615
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5401743
$484.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc204520
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Fas (TNF Receptor Superfamily, Member 6) (FAS)
- NCBI Accession:
- NM_000043,NP_000034
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5401745
$679.14
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr300253
RNAi
FAS
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- TNF Receptor Superfamily, Member 6
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3340047
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to FAS
- Fas cell surface death receptor (FAS)
- Fas (TNF receptor superfamily member 6) (Fas)
- Fas cell surface death receptor (Fas)
- Fas cell surface death receptor (fas)
- AI196731
- ALPS1A
- APO-1
- APO1
- APT1
- CD95
- FAS1
- FASTM
- lpr
- TNFR6
- TNFRSF6
- Tnfrsf6
Gene-IDs for different species
Protein level used designations for FAS
- APO-1 cell surface antigen
- CD95 antigen
- Delta Fas/APO-1/CD95
- FAS 827dupA
- FASLG receptor
- Fas (TNF receptor superfamily, member 6)
- Fas AMA
- TNF receptor superfamily member 6
- apoptosis antigen 1
- apoptosis-mediating surface antigen FAS
- tumor necrosis factor receptor superfamily member 6
- tumor necrosis factor receptor superfamily, member 6
- Fas antigen
- Fas (TNF receptor superfamily member)
- apo-1 antigen
- lymphoproliferation
- Fas antigen (ATP1)
- Fas receptor
- Tumor necrosis factor receptor superfamily, member 6
- apoptosis (APO-1) antigen 1 ( FAS ), member 6
- Fas receptor CD95
Proteomics products related to FAS Gene
Other products related to FAS such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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